Effects of swelling on the mechanical properties of a pH-sensitive hydrogel for use in microfluidic devices
Effects of swelling on the mechanical properties of a pH-sensitive hydrogel for use in microfluidic devices
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DOI：
10.1016/j.msec.2003.11.002
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发表时间：
2004-06-01
期刊：
影响因子：
--
通讯作者：
Crone, W
中科院分区：
文献类型：
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作者：
Johnson, BD;Beebe, DJ;Crone, W
拉伸试验进行了2-羟乙基甲基丙烯酸酯（HEMA）-丙烯酸（AA）共聚单体凝胶敏感的环境pH值的变化。机械性能（杨氏模量，泊松比，极限拉伸强度，断裂伸长率）进行了测定，在不同水平的溶胀平衡。在溶胀和未溶胀状态下测试的样品之间观察到极限拉伸强度（从300至60 kPa）和断裂伸长率百分比（从150%至30%）的变化。进行另外的测试以确定交联和聚合条件对机械性能的影响。将交联剂组分从0.2%增加至1%导致杨氏模量（34至380 kPa）增加一个数量级。研究发现，调整水凝胶的交联剂组分是控制力学性能的有效方法。(C)2003 Elsevier B. V.保留所有权利。
Tensile tests were conducted on a 2-hydroxyethyl methacrylate (HEMA)-acrylic acid (AA) comonomer gel sensitive to variations in environmental pH. Mechanical properties (Young's modulus, Poisson's ratio, ultimate tensile strength, and percent elongation at break) were determined at different levels of swelling equilibrium. Shifts in ultimate tensile strength (from 300 to 60 kPa) and percent elongation at break (from 150% to 30%) were observed between samples tested in the swollen and unswollen states. Additional tests were conducted to determine the effects of crosslinking and polymerization conditions on mechanical properties. Increasing the crosslinker component from 0.2% to 1% resulted in an increase in Young's modulus (34 to 380 kPa) by an order of magnitude. It is found that adjustment of the crosslinker component of the hydrogel is an effective method of controlling mechanical properties. (C) 2003 Elsevier B.V. All rights reserved.