Histologic analysis of prefabricated, vascularized bone grafts: An experimental study in rabbits
Histologic analysis of prefabricated, vascularized bone grafts: An experimental study in rabbits
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DOI：
10.1016/s0278-2391(00)90056-9
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发表时间：
2000-03-01
影响因子：
1.9
通讯作者：
Kesim, SN
中科院分区：
文献类型：
--
作者：
Celik, M;Tuncer, S;Kesim, SN
目的：探讨预制植骨材料的细胞质量。材料与方法：取11只1月龄幼兔，在耳背神经血管束周围放置小块髂骨，制作带血管预制移植物。在5只动物中，17个月后取预制骨进行组织学检查。第二组6只兔，以神经血管束为蒂，30天后将预制骨移植到面部右侧颧骨中部切除1厘米造成的缺损处。结果：两组移植骨均有丰富的血管网状结构，组织学特征与正常髂骨相似。结论：预制骨移植是一种潜在的骨重建材料。
Purpose: The purpose of this study was to investigate the cellular quality of prefabricated bone grafts.Materials and Methods: Small pieces of iliac bone were placed around the neurovascular bundle on the dorsal aspect of the ear of 11 one-month-old baby rabbits to create a prefabricated vascularized graft. In five animals, the prefabricated bone grafts were harvested for histologic examination 17 months later. In a second group of 6 rabbits, the prefabricated bone grafts, with the neurovascular bundle as a pedicle, were transferred after 30 days to a defect created by removing 1 cm of the midportion of zygoma on the right side of the face. The transferred bone Nas removed for histologic examination 11 months later.Results: In both groups, microscopic examination showed the presence of a rich, vascular network and similar histologic characteristics to those of normal iliac bone.Conclusion: The findings support the concept that prefabricated bone grafts are a potentially useful source for bony reconstruction.