Development and definition of a simplified scanning procedure and scoring method for Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US)
Development and definition of a simplified scanning procedure and scoring method for Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US)
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DOI：
10.1160/th12-11-0874
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发表时间：
2013-06-01
影响因子：
6.7
通讯作者：
Morfini, Massimo
中科院分区：
文献类型：
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作者：
Martinoli, Carlo;Alberighi, Ornella Della Casa;Morfini, Massimo
本研究的目的是开发一种简化的超声扫描程序和评分方法，称为血友病早期关节病超声检测 [HEAD-US]，以评估血友病关节病患者的关节。经过多学科专家小组初步达成共识的流程后，建立了三种全面且基于证据的肘部、膝部和踝部超声扫描程序，旨在提高检测关节受累早期迹象的灵敏度，同时保持技术简单、快速地执行。每个程序都包括对滑膜隐窝的系统评估和选择单个骨软骨表面进行损伤分析。根据专家共识，创建了一个基于附加量表的简化评分系统来定义关节状态，并从长远来看，为评估疾病进展和监测后续研究中的治疗结果提供工具。
The aim of this study was to develop a simplified ultrasound scanning procedure and scoring method, named Haemophilia Early Arthropathy Detection with UltraSound [HEAD-US], to evaluate joints of patients, with haemophilic arthropathy. After an initial consensus-based pro, cess involving a multidisciplinary panel of experts, three comprehensive and evidence-based US scanning procedures to image the elbow, knee and ankle were established with the aim to increase sensitivity in detection of early signs of joint involvement while keeping the technique easy and quick to perform. Each procedure included systematic evaluation of synovial recesses and selection of a single osteochondral surface for damage analysis. Based on expert consensus, a simplified scoring system based on an additive scale was created to define the joint status and, in perspective, to offer a tool to evaluate disease progression and monitor the result of treatment in follow-up studies.