3D structure of the macula flava in the human vocal fold
3D structure of the macula flava in the human vocal fold
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DOI：
10.1080/00016480310001123
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发表时间：
2003-01-01
影响因子：
1.4
通讯作者：
Nakashima, T
中科院分区：
文献类型：
--
作者：
Sato, K;Hirano, M;Nakashima, T
目的：探讨人声襞黄斑的三维结构。材料与方法：采用化学消解法（改良氢氧化钠浸渍法）对人声带黄斑的三维结构进行了扫描电镜观察，并与光镜观察结果进行了比较。结果：人声带黄斑由致密的细胞和细胞外基质组成。许多细胞呈星状，具有胞质突起。细胞外基质由胶原纤维、网状纤维和弹性纤维以及基质物质（透明质酸）组成。许多纤维向不同的方向伸展。星状细胞被这些细胞外基质包围。非晶材料附着在星状电池表面。黄斑的细胞外基质扩展到声带黏膜固有层的细胞外基质。结论：人声带黏膜前后黄斑可能参与细胞外基质的代谢，而细胞外基质对成人声带黏膜固有层（振动组织）的粘弹性至关重要。
Objective-To investigate the 3D structure of the macula flava in the human vocal fold.Material and Methods-The 3D structure of the macula flava in the human vocal fold was investigated by means of scanning electron microscopy using a chemical digestion method (modified sodium hydroxide maceration method) and the results compared with those obtained,using light microscopy.Results-The macula flava of the human vocal fold comprised a dense mass of cells and extracellular matrices. Many cells were stellate in shape and possessed cytoplasmic processes. Extracellular matrices were composed of collagenous, reticular and elastic fibers, and ground substances (hyaluronic acid). Many fibers ran in various directions. The stellate cells were surrounded by these extracellular matrices. Amorphous materials were attached to the surface of the stellate cells. Extracellular matrices in the macula flava extended to those in the lamina propria of them vocal fold mucosa.Conclusion-Anterior and posterior maculae flavae in the human vocal fold mucosa are postulated to be involved in the metabolism of extracellular matrices, which are essential to the viscoelasticity of the lamina propria (the vibrating tissue) of the human adult vocal fold mucosa.