relMix: An open source software for DNA mixtures with related contributors

relMix: An open source software for DNA mixtures with related contributors
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DOI:
10.1016/j.fsigss.2019.09.085
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发表时间:
2019-12-01
期刊:
FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES
影响因子:
--
通讯作者:
Egeland, Thore
Egeland, Thore
中科院分区:
其他
文献类型:
--
作者:
Hernandis, Elias;Dorum, Guro;Egeland, Thore

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在刑事案件和关系推断中,对涉及亲属的 DNA 混合物进行分析的需求日益增长。目标可能是确定混合物的贡献者,其中捐赠者可能相关或可能不相关,或者根据混合物确定个体之间的关系。 relMix 是一款用于分析涉及亲属的 DNA 混合物的开源软件,可在 R 中作为图形用户界面使用。我们解释了 relMix 背后的模型,并概述了最新版本中的新功能(包括改进的输入检查)。
In both criminal cases and relationship inference there is an increasing demand for analysis of DNA mixtures where relatives are involved. The goal might be to identify the contributors to a mixture where the donors may or may not be related, or to determine the relationship between individuals based on a mixture. relMix is an open source software for analysing DNA mixtures involving relatives, available as a graphical user interface in R. We explain the model behind relMix and give an overview of the new features (including improved checking of input) in the latest version.