High rates of the metabolic syndrome in a first nations community in western Canada: Prevalence and determinants in adults and children
High rates of the metabolic syndrome in a first nations community in western Canada: Prevalence and determinants in adults and children
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DOI：
10.3402/ijch.v65i5.18139
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发表时间：
2006-12-01
影响因子：
1.3
通讯作者：
Toth, Ellen L.
中科院分区：
文献类型：
--
作者：
Kaler, Sharpdeep Norry;Ralph-Campbell, Kelli;Toth, Ellen L.
目标。在北美各地的土著社区中，2型糖尿病的增加引发了对这些人群中代谢综合征的担忧。美国印第安人有一些患病率信息，但加拿大原住民的患病率信息很少。研究设计。我们对艾伯塔省单一第一民族60%的合格人口进行了糖尿病、糖尿病前期、心血管风险和代谢综合征的筛查。18岁的受试者采用NCEP/ATPIII和IDF标准来确定代谢综合征，18岁的受试者采用改良的NCEP/ATPIII标准。Logistic回归分析确定了与代谢综合征相关的因素。对297人进行了筛查(176名成年人，84名儿童/青少年，数据完整)。根据NCEP/ATPIII标准，52.3%的成年人患有代谢综合征，而根据IDF标准，50%的成年人患有代谢综合征。40.5%的年龄在18岁的人有这种情况。腰围是最常见的相关因素。双因素分析显示，年龄、BMI、体重、糖化血红蛋白、低密度脂蛋白胆固醇、ADA危险评分和活动方式与代谢综合征有关。我们的数据是西克里岛第一个可用的数据，与安大略省和马尼托巴省土著人口报告的流行率一致。18岁参与者肥胖、糖尿病前期和代谢综合征的高比率引发了人们对未来糖尿病和心血管疾病患病率的担忧。
Objectives. Increasing type 2 diabetes in Aboriginal communities across North America raises concerns about metabolic syndrome in these populations. Some prevalence information for American Indians exists, but little has been available for Canada's First Nations. Study Design. We screened 60% of the eligible Population of a single First Nation in Alberta for diabetes, prediabetes, cardiovascular risk, and metabolic syndrome.Methods. NCEP/ATP III and IDF criteria were used to identify metabolic syndrome in participants aged >= 18, modified NCEP/ATP III criteria were used for participants aged < 18. Logistic regression identified factors associated with the metabolic syndrome.Results. 297 individuals were screened (176 adults, 84 children/adolescents, with complete data). 52.3% of adults had metabolic syndrome using NCEP/ATP III criteria, and 50% using IDF criteria. 40.5 % of individuals aged < 18 had the condition. Waist circumference was the most prevalent correlate. Bivariate analysis suggested that age, BMI, weight, Alc, LDL-C, ADA risk score and activity pattern were associated with metabolic syndrome.Conclusions. Our data represent the first available for Western Cree and are consistent with prevalence reported for Aboriginal populations in Ontario and Manitoba. High rates of obesity, pre-diabetes and metabolic syndrome for participants aged < 18 raise concerns about future prevalence of diabetes and cardiovascular disease.