VALIDATION-STUDY OF SKULL 3-DIMENSIONAL COMPUTERIZED-TOMOGRAPHY MEASUREMENTS
VALIDATION-STUDY OF SKULL 3-DIMENSIONAL COMPUTERIZED-TOMOGRAPHY MEASUREMENTS
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DOI：
10.1002/ajpa.1330820307
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发表时间：
1990-07-01
影响因子：
2.8
通讯作者：
KNAPP, RH
中科院分区：
文献类型：
--
作者：
HILDEBOLT, CF;VANNIER, MW;KNAPP, RH
成像技术的最新进展带来了高分辨率计算机断层扫描 (CT) 扫描，可提供精美详细的颅骨切片图像，并使用计算机软件进行三维 (3-D) 表面重建。可以使用 CT 扫描以方便的数字形式获取头骨的形态信息，并从表面重建图像中获取 3D 测量结果。不幸的是，迄今为止，还没有做出任何努力来测试实验室样本上这些测量的有效性，也没有从模型研究中获得令人信服的证据来表明测量技术固有误差的性质和程度。我们进行了一项试点研究，根据 CT 扫描和 3D 重建中发现的表面特征来量化头骨的形态。使用卡尺和 3D 电磁数字化仪对五个头骨（两个正常，三个畸形）进行了比较测量。这些测量结果与基于原始 CT 扫描切片和重新格式化的 3D 图像的测量结果进行了统计比较。结论是，3D-CT 测量技术优于直接从原始 CT 切片获得测量结果的技术；然而，在基于这些技术的测量可用于需要高精度的研究之前，必须显着改进 3D CT 方法。结果用于表明未来研究最富有成果的领域。
Recent advances in imaging have led to high‐resolution computerized tomography (CT) scanning with exquisitely detailed slice images of the skull and three‐dimensional (3‐D) surface reconstructions using computer software. It is possible to use CT scans to acquire morphologic information about the skull in a convenient digital form and to derive 3‐D measurements from surface reconstruction images. Unfortunately, no effort has been made to date to test the validity of these measurements on laboratory specimens, and no compelling evidence is available from phantom studies to indicate the nature and magnitude of the errors inherent in the measurement technique. We have performed a pilot study to quantify the morphology of the skull based on surface features that can be found in CT scans and 3‐D reconstructions. Comparative measurements were obtained from five skulls (two normal and three with dysmorphology) with calipers and a 3‐D electromagnetic digitizer. These measurements were statistically compared with those based on original CT scan slices and reformatted 3‐D images. It is concluded that 3D‐CT measurements techniques are superior to those in which measurements are obtained directly from the original CT slices; 3‐D CT methods, however, must be significantly improved before measurements based on these techniques can be used in studies that require a high degree of precision. The results are used to indicate the most fruitful areas of future study.