Objective assessment of induced acute pain in neonatology with the Newborn Infant Parasympathetic Evaluation index
Objective assessment of induced acute pain in neonatology with the Newborn Infant Parasympathetic Evaluation index
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DOI：
10.1002/ejp.1191
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发表时间：
2018-07-01
影响因子：
3.6
通讯作者：
Patural, H.
中科院分区：
文献类型：
--
作者：
Cremillieux, C.;Makhlouf, A.;Patural, H.
背景需要客观的工具来改善新生儿疼痛评估。本研究的目的是评估新生儿副交感神经评价（NIPE）指数和两个疼痛量表在一个痛苦的程序在早产儿。Methodeach婴儿出生至少在26周的胎龄（GA）进行计划的痛苦的程序在新生儿重症监护室（NICU）之间的相关性是合格的。分别于麻醉前5 min（T1）、麻醉过程中（T2）和麻醉结束后3 min（T3）记录NIPE指数、心率变异性（HRV）指数和新生儿急性疼痛评分（DAN）。在T2时记录早产儿疼痛量表（PIPP-R）。结果29例早产儿共记录64次，平均GA= 29.94.2周。将28个速度描记图与NIPE结合进行分析。在疼痛时间T2，我们没有发现NIPE指数与DAN和PIPP-R之间的相关性。在T1和T2之间，心率更高（15916 vs. 169 +/- 12，p
BackgroundObjective tools are needed to improve pain assessment in newborns. The aim of this study was to assess the correlation between the Newborn Infant Parasympathetic Evaluation (NIPE) index and two pain scales during a painful procedure in premature infants.MethodEach baby born at least at 26weeks of gestational age (GA) undergoing a planned painful procedure in the Neonatal Intensive Care Unit (NICU) was eligible. NIPE index, heart rate variability (HRV) indices and Neonatal Acute Pain scale (DAN) were recorded across three periods: the first at rest 5min before the painful procedure (T1), the second during it (T2) and the third 3min after the end of it (T3). The Premature Infant Pain Profile-Revised (PIPP-R) pain scale was recorded at T2.ResultsSixty-four recordings were performed in 29 preterm infants (mean GA=29.94.2weeks). Twenty-eight tachograms were coupled to NIPE for analysis. We did not find a correlation between the NIPE index and DAN and PIPP-R at the pain time T2. Between T1 and T2, heart rate was higher (15916 vs. 169 +/- 12, p