A randomized, double-blind trial of bromocriptine efficacy in nonfluent aphasia after stroke

A randomized, double-blind trial of bromocriptine efficacy in nonfluent aphasia after stroke
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DOI:
10.1212/01.wnl.0000203119.91762.0c
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发表时间:
2006-03-28
期刊:
影响因子:
9.9
通讯作者:
Bahrami, A
Bahrami, A
中科院分区:
医学1区
文献类型:
--
作者:
Ashtary, F;Janghorbani, M;Bahrami, A

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作者在2002年6月至2004年4月进行的一项为期16周的随机、双盲、安慰剂对照临床试验中评估了溴隐亭治疗卒中后非流利性失语症的疗效。在治疗4个月后的所有38名患者中,观察到溴隐亭和安慰剂治疗组的改善(p < 0.001)。重复测量的方差分析显示溴隐亭并没有改善非流利性失语症。
The authors assessed the efficacy of bromocriptine in nonfluent aphasia after stroke in a 16-week, randomized, double-blind, placebo-controlled clinical trial conducted from June 2002 to April 2004. In all 38 patients after 4 months of treatment, improvement in both the bromocriptine and placebo treatment groups was observed (p < 0.001). The analysis of repeated-measures analysis of variance revealed bromocriptine did not improve nonfluent aphasia.