Egg consumption as part of an energy-restricted high-protein diet improves blood lipid and blood glucose profiles in individuals with type 2 diabetes
Egg consumption as part of an energy-restricted high-protein diet improves blood lipid and blood glucose profiles in individuals with type 2 diabetes
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DOI：
10.1017/s0007114510003983
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发表时间：
2011-02-01
影响因子：
3.6
通讯作者：
Noakes, Manny
中科院分区：
文献类型：
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作者：
Pearce, Karma L.;Clifton, Peter M.;Noakes, Manny
饮食中胆固醇在糖尿病患者中的作用很少被研究。我们研究了低能量高蛋白高胆固醇（HPHchol）饮食与相似量的动物蛋白（高蛋白低胆固醇，HPLchol）对2型糖尿病患者血脂、血糖控制和心血管风险标志物的影响。共有65名2型糖尿病或糖耐量受损受试者（年龄54.4（SD 8.2）岁; BMI 34.1（SD 4.8）kg/m2; LDL-胆固醇（LDL-C）2.67（SD 0.10）mmol/l）被随机分配至HPHchol或HPLchol组。低能量饮食干预（6-7 MJ; 1.4-1.7 Mcal）和总碳水化合物：蛋白质：脂肪比例为40：30：30%相似，但胆固醇含量不同（HPHchol，590 mg胆固醇; HPLchol，213 mg胆固醇）。HPHchol参与者每天消耗两个鸡蛋，而HPHchol参与者用100 g瘦肉动物蛋白代替鸡蛋。12周后体重下降6.0（SD 0.4）kg（P
The role of dietary cholesterol in people with diabetes has been little studied. We investigated the effect of a hypoenergetic high-protein high-cholesterol (HPHchol) diet compared to a similar amount of animal protein (high-protein low-cholesterol, HPLchol) on plasma lipids, glycaemic control and cardiovascular risk markers in individuals with type 2 diabetes. A total of sixty-five participants with type 2 diabetes or impaired glucose tolerance (age 54.4 (SD 8.2) years; BMI 34.1 (SD 4.8) kg/m(2); LDL-cholesterol (LDL-C) 2.67 (SD 0.10) mmol/l) were randomised to either HPHchol or HPLchol. Both hypoenergetic dietary interventions (6-7 MJ; 1.4-1.7 Mcal) and total carbohydrate: protein: fat ratio of 40:30:30% were similar but differed in cholesterol content (HPHchol, 590mg cholesterol; HPLchol, 213mg cholesterol). HPHchol participants consumed two eggs per d, whereas HPHchol participants replaced the eggs with 100 g of lean animal protein. After 12 weeks, weight loss was 6.0 (SD 0.4) kg (P