Medium-dose intravenous immunoglobulin therapy for women with six or more recurrent miscarriages
Medium-dose intravenous immunoglobulin therapy for women with six or more recurrent miscarriages
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DOI：
10.1016/j.jri.2015.01.008
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发表时间：
2015-06-01
影响因子：
3.4
通讯作者：
Ebina, Yasuhiko
中科院分区：
文献类型：
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作者：
Yamada, Hideto;Deguchi, Masashi;Ebina, Yasuhiko
本研究旨在评估接受中等剂量静脉注射免疫球蛋白（IVIg）治疗的复发性流产妇女的自然杀伤（NK）细胞活性和单核细胞百分比的变化。14名有6次或6次以上不明原因反复流产史的妇女在妊娠早期接受了60 g IVIg治疗（每天20 g，持续3天）。NI（外周血细胞活性治疗后1周较治疗前下降12%（中位数22%，P
This study aimed to evaluate changes in natural killer (NK) cell activity and the percentage of monocytes in women with recurrent miscarriage who received medium-dose intravenous immunoglobulin (IVIg) therapy. Fourteen women with a history of six or more recurrent miscarriages of unexplained etiology received 60-g IVIg therapy (20 g daily, for three days) during early gestation. NI( cell activity in the peripheral blood decreased to 12% one week after therapy compared with before therapy (median, 22%, P