Elevated body mass index and mortality risk in the elderly
Elevated body mass index and mortality risk in the elderly
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DOI：
10.1111/j.1467-789x.2006.00248.x
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发表时间：
2007-01-01
期刊：
影响因子：
8.9
通讯作者：
Mark, A. E.
中科院分区：
文献类型：
--
作者：
Janssen, I.;Mark, A. E.
本报告的目的是对研究体重指数（BMI）升高对老年（≥ 65岁）男性和女性死亡风险的影响的研究进行系统回顾和荟萃分析。使用基于方差的荟萃分析方法总结现有研究中的关系。来自26项分析的全因死亡率的汇总相对风险为1.00（95%置信区间，0.97-1.03），这些分析包括BMI在超重范围内的风险估计。28项分析的全因死亡率的汇总相对风险为1.10（1.06-1.13），其中包括肥胖范围内BMI的风险估计。这些计算表明，超重范围内的BMI与老年人死亡风险的显著增加无关，而中度肥胖范围内的BMI仅与死亡风险的适度增加相关。
The purpose of this report was to perform a systematic review and meta-analysis of the studies examining the impact of an elevated body mass index (BMI) on mortality risk in elderly (>= 65 years) men and women. A variance-based method of meta-analysis was used to summarize the relationships from available studies. The summary relative risk of all-cause mortality from the 26 analyses that included a risk estimate for a BMI within the overweight range was 1.00 (95% confidence intervals, 0.97-1.03). The summary relative risk of all-cause mortality for the 28 analyses that included a risk estimate for a BMI within the obese range was 1.10 (1.06-1.13). These calculations indicate that a BMI in the overweight range is not associated with a significantly increased risk of mortality in the elderly, while a BMI in the moderately obese range is only associated with a modest increase in mortality risk.