DEVELOPMENT OF RAT FLEXOR DIGITAL TENDON A FINE STRUCTURE STUDY
DEVELOPMENT OF RAT FLEXOR DIGITAL TENDON A FINE STRUCTURE STUDY
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DOI：
10.1016/s0022-5320(67)80124-2
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发表时间：
1967-01-01
期刊：
影响因子：
--
通讯作者：
ROSS, R
中科院分区：
文献类型：
--
作者：
GREENLEE, TK;ROSS, R
在胎儿和出生后的大鼠中，研究了后足滑膜鞘屈肌腱的发育。肌腱最初是在16天的胎儿中被鉴定为离散的细胞集合。滑膜鞘形成开始于18天胎仔，并在出生时完成。在形成肌腱的细胞之间和内脏滑膜细胞之间观察到细胞连接或粘附部位。然而，在这两个不同群体的细胞之间没有观察到连接。生长力和细胞粘附维持结构完整性之间的相互作用可以解释肌腱内特定结构实体的发展。在12天的胎儿中，主要含有游离胞质核糖体的低分化间充质细胞分化为具有突出的粗糙表面内质网和高尔基复合体的肌腱成纤维细胞。除了细胞外间隙中的胶原纤维外，还鉴定了小弹性纤维，并在其发育中进行了跟踪。
The development of hind feet synovial sheath flexor tendons has been examined in fetal and postnatal rats. The tendons were first identified as discrete collections of cells in 16-day fetuses. Synovial sheath formation had commenced in 18-day fetuses and was complete by birth. Cell junctions or adhesion sites were noted between the cells that form the tendon proper and between the cells of the visceral synovium. However, no junctions were observed between the cells of these two different populations. The interaction between growth forces and the maintenance of structural integrity by cell adhesions may explain the development of specific structural entities within the tendon. Poorly differentiated mesenchymal cells in 12-day fetuses containing predominantly free cytoplasmic ribosomes differentiate into tendon fibroblasts with a prominent rough-surfaced endoplasmic reticulum and Golgi complex. Besides collagen fibrils in the extracellular space small elastic fibers were also identified and followed in their development.