The interaction of UVA and UVB in the production of threshold erythema.
The interaction of UVA and UVB in the production of threshold erythema.
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UVA 和 UVB 在阈值红斑产生中的相互作用。
DOI：
10.1111/1523-1747.ep12507481
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Parrish,JA
中科院分区：
文献类型：
--
作者：
Paul,BS;Parrish,JA
一项研究已经完成，以定量和图形的方式证明，在亚致红剂量的宽带UVA和UVB相互作用，产生一个可见的红斑。在皮肤白皙的志愿者背部，测定了多色UVA和UVB的最小红斑剂量（MED）。在已经暴露于不同分量的中波紫外线辐射的地方，不断增加的长波紫外线辐射剂量导致暴露于不同剂量的长波紫外线和中波紫外线的地方。把波段的顺序颠倒过来，重复了同样的实验。结果表明，当UVA之后是UVB时，在这些部分的总和等于1的地方会产生红斑，这种相互作用称为光加法。当UVA暴露在UVB之后，红斑再次主要出现在那些显示光附加的部位。然而，在后一种情况下，注意到分数之和大于1的许多阈值红斑。这提示光恢复。两种曝光顺序均未观察到光增强的证据。
A study was done to demonstrate quantitatively and graphically the way in which suberythemogenic doses of broadband UVA and UVB interact in producing a visible erythema. On the backs of fair-skinned human volunteers the minimal erythema dose (MED) was determined for polychromatic UVA and UVB. Increasing fractions of the UVA MED were given to sites already exposed to various fractions of the UVB MED resulting in sites exposed to various doses of both UVA and UVB. The same experiment was repeated with the order of wave- bands reversed. It was demonstrated that when UVA was followed by UVB an erythema was produced in those sites where the sum of the fractions was equal to one, an interaction termed photoaddition. When the UVA exposure followed the UVB, erythema was again predominantly noted in those sites demonstrating photoaddition. However, in the latter case, numerous sites of threshold erythema were noted where the sum of the fractions was greater than one. This is suggestive of photorecovery. No evidence of photoaugmentation was observed with either order of exposure.