Effects of External Radiation Exposure Resulting From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey.
Effects of External Radiation Exposure Resulting From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey.
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DOI：
10.2188/jea.je20210286
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发表时间：
2022
影响因子：
4.7
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中科院分区：
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据报道，生活方式相关疾病与东日本大地震（GEJE）后的疏散之间存在关联。然而，生活方式相关疾病和GEJE后外照射有效辐射剂量（EDEE）之间的关系仍不清楚。在2011年度接受全面健康检查的福岛县72,869名居民（男性31,982人、女性40,887人）中，对16 ~ 84岁的54,087名居民（男性22,599人、女性31,488人）的数据进行了分析。为估计外照射剂量而进行的基本调查结果不完整的25 685名居民的EDEE数据，使用多重插补进行了补充。根据EDEE将数据分为三组（0至<1、1至<2和≥2 mSv组），并使用考克斯比例风险模型（以2011财年为基线）检查2011财年至2017财年疾病发生率与EDEE之间的相关性。在年龄和性别校正模型中，从2011财年至2017财年，EDEE较高与高血压、糖尿病、血脂异常、高尿酸血症、肝功能障碍和红细胞增多症的发生率较高相关。然而，在进一步调整疏散状态和生活方式相关因素后，显着关联消失。未发现EDEE与其他生活方式相关疾病之间存在关联。EDEE与GEJE后生活方式相关疾病的发生率没有直接关系。然而，在福岛县，外部辐射剂量较高的居民可能会患上与疏散和由此产生的生活方式改变有关的生活方式疾病。
Associations have been reported between lifestyle-related diseases and evacuation after the Great East Japan Earthquake (GEJE). However, the relationship between lifestyle-related diseases and the effective radiation dose due to external exposure (EDEE) after the GEJE remains unclear. From among 72,869 residents of Fukushima Prefecture (31,982 men; 40,887 women) who underwent a comprehensive health check in fiscal year (FY) 2011, the data of 54,087 residents (22,599 men; 31,488 women) aged 16 to 84 years were analyzed. The EDEE data of 25,685 residents with incomplete results from the basic survey, performed to estimate the external radiation exposure dose, were supplemented using multiple imputation. The data were classified into three groups based on EDEE (0 to <1, 1 to <2, and ≥2 mSv groups and associations between the incidence of diseases and EDEE from FY2011 to FY2017 were examined using a Cox proportional hazards model, with FY2011 as the baseline. A higher EDEE was associated with a greater incidence of hypertension, diabetes mellitus, dyslipidemia, hyperuricemia, liver dysfunction, and polycythemia from FY2011 to FY2017 in the age- and sex-adjusted model. However, after further adjustment for evacuation status and lifestyle-related factors, the significant associations disappeared. No association was found between EDEE and other lifestyle-related diseases. EDEE was not directly associated with the incidence of lifestyle-related diseases after the GEJE. However, residents with higher external radiation doses in Fukushima Prefecture might suffer from lifestyle-related diseases related to evacuation and the resultant lifestyle changes.