Enhanced 'Reading the Mind in the Eyes' in borderline personality disorder compared to healthy controls.

Enhanced 'Reading the Mind in the Eyes' in borderline personality disorder compared to healthy controls.
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DOI:
10.1017/s003329170900600x
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发表时间:
2009-12
影响因子:
6.9
通讯作者:
Stanley B
Stanley B
中科院分区:
医学1区
文献类型:
--
作者:
Fertuck EA;Jekal A;Song I;Wyman B;Morris MC;Wilson ST;Brodsky BS;Stanley B

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边缘型人格障碍(BPD)的部分特征是人际关系的长期不稳定,这加剧了该障碍的其他症状,并可能干扰治疗参与。面部情绪识别范式已被用来调查BPD中人际功能障碍的基础,产生混合的结果。我们试图通过阅读眼睛中的思想测试(RMET)来澄清和扩展过去的发现,RMET是一种衡量从面部眼睛区域的表情中区分他人精神状态的能力的方法。将30名诊断为BPD的个体与25名健康对照(HC)进行RMET性能比较。参与者还评估了抑郁症的严重程度,评估时的情绪状态,童年虐待史,以及其他轴I和人格障碍(PD)。BPD组在RMET上的表现明显优于HC组,特别是在总分和中性情绪效价方面。总评分和中性RMET性能的效应量范围较大。这些结果无法通过人口统计学、共同发生的轴I或轴II疾病、药物状态、滥用史或情绪状态来解释。然而,抑郁的严重程度部分介导的关系RMET和BPD状态。在BPD中,基于面部眼睛区域的心理状态辨别被增强。对他人心理状态的敏感性增强可能是BPD社会功能障碍的基础。
Borderline personality disorder (BPD) is partly characterized by chronic instability in interpersonal relationships, which exacerbates other symptom dimensions of the disorder and can interfere with treatment engagement. Facial emotion recognition paradigms have been used to investigate the bases of interpersonal impairments in BPD, yielding mixed results. We sought to clarify and extend past findings by using the Reading the Mind in the Eyes Test (RMET), a measure of the capacity to discriminate the mental state of others from expressions in the eye region of the face. Thirty individuals diagnosed with BPD were compared to 25 healthy controls (HCs) on RMET performance. Participants were also assessed for depression severity, emotional state at the time of assessment, history of childhood abuse, and other Axis I and personality disorders (PDs). The BPD group performed significantly better than the HC group on the RMET, particularly for the Total Score and Neutral emotional valences. Effect sizes were in the large range for the Total Score and for Neutral RMET performance. The results could not be accounted for by demographics, co-occurring Axis I or II conditions, medication status, abuse history, or emotional state. However, depression severity partially mediated the relationship between RMET and BPD status. Mental state discrimination based on the eye region of the face is enhanced in BPD. An enhanced sensitivity to the mental states of others may be a basis for the social impairments in BPD.