Silicon nanohybrid-based surface-enhanced Raman scattering sensors.
Silicon nanohybrid-based surface-enhanced Raman scattering sensors.
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DOI：
10.1002/smll.201401563
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发表时间：
2014-11
期刊：
影响因子：
13.3
通讯作者：
Houyu Wang;Xiangxu Jiang;Shuitong Lee;Yao He
中科院分区：
文献类型：
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作者：
Houyu Wang;Xiangxu Jiang;Shuitong Lee;Yao He
基于纳米材料的表面增强拉曼散射(SERS)传感器是一种非常有前途的分析工具，能够对化学和生物物种进行超灵敏、多重和无损检测。人们已经做出了广泛的努力来设计各种基于硅纳米杂化的SERS衬底，如金/银纳米颗粒(NP)修饰的硅纳米线、Au/Ag纳米颗粒修饰的硅片(AuNP@Si)等。与不含AuNP和AgNP的SERS传感器相比，基于硅纳米杂化的SERS传感器具有更高的增强因子(EFS)和良好的重复性，因为SERS热点通过与半导体硅衬底的互连有效地耦合和稳定。因此，在过去的十年里，基于硅纳米杂化的SERS传感器的发展取得了巨大的进步，用于无数的传感应用。本文对高性能硅纳米杂化SERS传感器的设计及其在化学和生物分析中的应用等方面的代表性成果进行了详细的综述。此外，还从广泛的角度讨论了该领域的主要机遇和挑战以及未来可能的发展方向。
Nanomaterial-based surface-enhanced Raman scattering (SERS) sensors are highly promising analytical tools, capable of ultrasensitive, multiplex, and nondestructive detection of chemical and biological species. Extensive efforts have been made to design various silicon nanohybrid-based SERS substrates such as gold/silver nanoparticle (NP)-decorated silicon nanowires, Au/Ag NP-decorated silicon wafers (AuNP@Si), and so forth. In comparison to free AuNP- and AgNP-based SERS sensors, the silicon nanohybrid-based SERS sensors feature higher enhancement factors (EFs) and excellent reproducibility, since SERS hot spots are efficiently coupled and stabilized through interconnection to the semiconducting silicon substrates. Consequently, in the past decade, giant advancements in the development of silicon nanohybrid-based SERS sensors have been witnessed for myriad sensing applications. In this review, the representative achievements related to the design of high-performance silicon nanohybrid-based SERS sensors and their use for chemical and biological analysis are reviewed in a detailed way. Furthermore, the major opportunities and challenges in this field are discussed from a broad perspective and possible future directions.