Study methods, recruitment, sociodemographic findings, and demographic representativeness in the OPPERA study.
Study methods, recruitment, sociodemographic findings, and demographic representativeness in the OPPERA study.
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DOI:
10.1016/j.jpain.2011.08.001
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发表时间:
2011-11
期刊:
影响因子:
--
通讯作者:
Ohrbach R
中科院分区:
文献类型:
--
作者:
Slade GD;Bair E;By K;Mulkey F;Baraian C;Rothwell R;Reynolds M;Miller V;Gonzalez Y;Gordon S;Ribeiro-Dasilva M;Lim PF;Greenspan JD;Dubner R;Fillingim RB;Diatchenko L;Maixner W;Dampier D;Knott C;Ohrbach R
This paper describes methods used in the project “Orofacial Pain Prospective Evaluation and Risk Assessment” (OPPERA) and evaluates socio-demographic characteristics associated with temporomandibular disorders (TMD) in the OPPERA case-control study. Representativeness was investigated by comparing socio-demographic profiles of OPPERA participants with population census profiles of counties near study sites and by comparing age- and gender-associations with TMD in OPPERA and the 2007-09 US National Health Interview Survey. Volunteers aged 18-44 years were recruited at four US study sites: 3,263 people without TMD were enrolled into the prospective cohort study; 1,633 of them were selected as controls for the baseline case-control study. Cases were 185 volunteers with examiner-classified TMD. Distributions of some demographic characteristics among OPPERA participants differed from census profiles, although there was less difference in socio-economic profiles. Odds of TMD was associated with greater age in this 18-44 year range; females had three times the odds of TMD as males; and relative to non-Hispanic-Whites, other racial groups had one-fifth the odds of TMD. Age- and gender-associations with chronic TMD were strikingly similar to associations observed in the US population. Assessments of representativeness in this demographically diverse group of community volunteers suggest that OPPERA case-control findings have good internal validity.
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