Intraoral somatosensory abnormalities in patients with atypical odontalgia--a controlled multicenter quantitative sensory testing study.

Intraoral somatosensory abnormalities in patients with atypical odontalgia--a controlled multicenter quantitative sensory testing study.
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DOI:
10.1016/j.pain.2013.04.005
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发表时间:
2013-08
期刊:
影响因子:
7.4
通讯作者:
Svensson P
Svensson P
中科院分区:
医学1区
文献类型:
--
作者:
Baad-Hansen L;Pigg M;Ivanovic SE;Faris H;List T;Drangsholt M;Svensson P

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根据最新指南,非典型牙痛(AO)患者的口内体感敏感性尚未进行系统研究。本研究的目的是:1。以健康受试者为参照,检查AO患者口内体感障碍。评估口内定量感觉测试(QST)和定性感觉测试(QualST)之间的一致性百分比。在华盛顿大学、马尔默大学和奥尔胡斯大学纳入了47例AO患者和69例健康对照。在AO患者中,在疼痛部位、相应的对侧部位和鱼际进行口内体感测试。在健康受试者,口内体感测试进行双侧上前磨牙牙龈和鱼际。在每个研究中心评价了13个QST和3个QualST参数,基于健康参考材料计算AO患者的z评分,并创建LossGain评分。AO患者QST异常率为87.3%。AO患者中最常见的体感异常是疼痛机械和冷刺激的体感增益以及冷检测和机械检测的体感丢失。最常见的LossGain代码为L0G2(无躯体感觉丧失,机械躯体感觉功能获得)(31.9%的AO患者)。AO患者相应的QST和QualST测量的热敏感性和机械敏感性之间的一致性百分比范围为55.6%至70.4%,对照组为71.1%至92.1%。总之,AO患者口内体感异常常见,定量和定性感觉测试之间的一致性为良好至极佳。
Intraoral somatosensory sensitivity in patients with atypical odontalgia (AO) has not been investigated systematically according to the most recent guidelines. The aims of this study were to: 1. Examine intraoral somatosensory disturbances in AO patients using healthy subjects as reference and 2. Evaluate the percent agreement between intraoral quantitative sensory testing (QST) and qualitative sensory testing (QualST). Forty-seven AO patients and 69 healthy controls were included at Universities of Washington, Malmö and Aarhus. In AO patients, intraoral somatosensory testing was performed on the painful site, the corresponding contralateral site and at thenar. In healthy subjects, intraoral somatosensory testing was performed bilaterally on the upper premolar gingiva and at thenar. Thirteen QST and 3 QualST parameters were evaluated at each site, z-scores were computed for AO patients based on the healthy reference material and LossGain scores were created. 87.3% of AO patients had QST abnormalities compared with controls. The most frequent somatosensory abnormalities in AO patients were somatosensory gain with regard to painful mechanical and cold stimuli and somatosensory loss with regard to cold detection and mechanical detection. The most frequent LossGain code was L0G2 (no somatosensory loss with gain of mechanical somatosensory function)(31.9% of AO patients). Percent agreement between corresponding QST and QualST measures of thermal and mechanical sensitivity ranged between 55.6 and 70.4% in AO patients and between 71.1 and 92.1% in controls. In conclusion, intraoral somatosensory abnormalities were commonly detected in AO patients and agreement between quantitative and qualitative sensory testing was good to excellent.
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