Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: a randomized, controlled pilot study.
Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: a randomized, controlled pilot study.
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每日蔓越莓汁预防妊娠期无症状菌尿：一项随机对照试点研究。
DOI：
10.1016/j.juro.2008.06.016
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发表时间：
2008-10
期刊：
影响因子：
--
通讯作者：
Chung JH
中科院分区：
文献类型：
--
作者：
Wing DA;Rumney PJ;Preslicka CW;Chung JH
To compare daily cranberry juice cocktail to placebo during pregnancy on asymptomatic bacteriuria (ASB) and symptomatic urinary tract infections (UTIs). 188 women were randomized to cranberry or placebo in three treatment arms: A: Cranberry three times daily (n=58), B: Cranberry at breakfast, then placebo at lunch and dinner (n=67), C. Placebo three times daily (n=63). After 27.7% (52/188) of the subjects were enrolled, the dosing regimens were changed to twice daily dosing to improve compliance. There were 27 UTIs in 18 subjects in this cohort: 6 in 4 subjects in Group A, 10 in 7 subjects in Group B, and 11 in 7 subjects in Group C, p=0.71. There were 57% and 41% reductions in the frequency of ASB and all UTIs in the multiple daily dosing group, however, this study was not sufficiently powered at the alpha 0.05 level (CI 0.14–1.39 and 0.22–1.60, respectively, incidence rate ratios). 73/188 (38.8%) subjects withdrew, most for gastrointestinal upset. These data suggest there may be a protective effect of cranberry ingestion against ASB and symptomatic UTIs in pregnancy. Further studies are planned to evaluate this effect.
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影响因子：
--
作者：
KASS, EH
通讯作者：
KASS, EH
影响因子：
6.7
作者：
McMurdo, MET;Bissett, LY;Crombie, IK
通讯作者：
Crombie, IK
影响因子：
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作者：
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通讯作者：
DeVivo, MJ
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作者：
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通讯作者：
Vorsa, N
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作者：
STENQVIST, K;DAHLENNILSSON, I;SVANBORGEDEN, C
通讯作者：
SVANBORGEDEN, C