Biomodification to dentin by a natural crosslinker improved the resin-dentin bonds
Biomodification to dentin by a natural crosslinker improved the resin-dentin bonds
复制标题
通过天然交联剂对牙本质进行生物改性改善了树脂-牙本质的结合
DOI：
10.1016/j.jdent.2012.02.008
复制
发表时间：
2012-06-01
影响因子：
4.4
通讯作者：
Chen, Jihua
中科院分区：
文献类型：
--
作者：
Fang, Ming;Liu, Ruirui;Chen, Jihua
目的：天然交联剂原花青素（PA）对脱矿牙本质进行瞬时胶原交联处理，可提高脱矿牙本质的交联度和抗张强度。本研究的目的是调查是否短暂的预处理PA基预处理剂可以改善树脂牙本质粘结的各种酸蚀和冲洗粘合剂。溶剂类型，PA浓度和治疗持续时间的影响进行了examined.Methods：PA为基础的预处理剂，通过添加粉末状葡萄籽提取物，富含PA，各种溶剂在不同的浓度。在应用粘合剂之前，将其用于脱矿牙本质。粘结强度，故障模式和程度的转换进行了评价，通过微拉伸测试，场发射扫描电子显微镜和傅立叶变换红外spectroscopics.Results：胶原交联处理PA为基础的预处理提出了浓度和时间依赖性增加牙本质粘结强度，即使在减少，临床适用的治疗时间。PA预处理改善测试的水/乙醇基粘合剂的粘结强度优于水/丙酮基系统。混合断裂是最常见的破坏模式发生在混合层的顶部在PA预处理的标本，而在底部的未处理的对照。PA pretreatment.Conclusions：瞬时PA预处理改善树脂牙本质的债券，而不损害测试粘合剂的固化行为的转换程度没有显着影响。(C)2012爱思唯尔有限公司保留所有权利。
Objectives: Transient collagen cross-linking treatment by proanthocyanidins (PA), a natural crosslinker, was proved to increase the cross-linking degree and ultimate tensile strength of demineralised dentin. The present study aimed to investigate whether transient pretreatment by PA-based preconditioner can improve the resin-dentin bonds of various etch and rinse adhesives. The influence of solvent type, PA concentration and treatment duration were examined.Methods: PA-based preconditioners were prepared by adding powdered grape seed extract, rich in PA, to various solvents at different concentrations. They were used on demineralised dentin before the application of the bonding agent. Bond strength, failure modes and degree of conversion were evaluated via microtensile testing, field emission scanning electron microscopy and Fourier transform infrared spectroscopy, respectively.Results: Collagen cross-linking treatment by PA-based preconditioners presented a concentration- and time-dependent increase in dentin bond strength even in reduced, clinically applicable treatment duration. PA preconditioning improved bond strength of the tested water/ethanol-based adhesive better than the water/acetone-based system. Mixed fracture was the most prevalent failure mode happened on the top of the hybrid layer in PA-pretreated specimens, whilst at the bottom in non-treated controls. The degree of conversion was not significantly affected by PA pretreatment.Conclusions: Transient PA preconditioning improved resin-dentin bonds without compromise on the curing behaviours of the tested adhesives. (C) 2012 Elsevier Ltd. All rights reserved.