Visuo-spatial neural response interactions in early cortical processing during a simple reaction time task: a high-density electrical mapping study
Visuo-spatial neural response interactions in early cortical processing during a simple reaction time task: a high-density electrical mapping study
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DOI：
10.1016/s0028-3932(01)00004-5
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发表时间：
2001-01-01
期刊：
影响因子：
2.6
通讯作者：
Schroeder, CE
中科院分区：
文献类型：
--
作者：
Murray, MM;Foxe, JJ;Schroeder, CE
研究了15名受试者不同视觉象限对刺激反应相互作用的时间过程和头皮地形图。在一项简单反应时(RT)任务中，从电极记录视觉诱发电位(VEP)。对不同象限中显示的单个刺激的VEP进行求和(“SUM”)，并与相同两个象限同时刺激的VEP反应(“对”)进行比较。如果对单个刺激的神经反应是独立的，这些反应将是等同的。“对”和“和”VEP之间的差异表明存在神经反应交互作用。在每个视野中。相互作用发生在刺激后72-86ms内的顶枕脑区。与视觉象限无关，刺激对的反应时比单刺激的反应时快。这复制了双侧刺激对观察到的冗余目标效应(RTE)，并将RTE推广到单侧刺激对。使用Miller的种族模型不等式(Miller J.Divided Attify：Evidience for Coactive With Redundant Signals)，我们发现概率总和可以完全解释每个视野中的RTE。尽管从电压波形的测量结果复制了早期峰值P1潜伏期的观测结果，但在“配对”与“总和”比较中(Miniussi C，Girelli M，Marzi CA.冗余靶点效应的神经部位：电生理学证据。认知神经科学杂志1998，10：216-30)，这不适用于从二阶导数(头皮电流密度)波形进行的测量。因为双侧刺激对的相互作用效应发生在86ms内，需要大脑半球间的转移。经颧骨截击必须在86ms内到达，这比先前计算的时间要早。与单边条件相比，双边条件下的交互作用延迟了大约10ms。与目前对大脑半球间传播时间的估计一致。相互作用效应对神经元集合合并来自视觉空间不同象限的输入所需的时间设置了上限(单侧条件下约为72ms，双边条件下约为82ms)。(C)2001爱思唯尔科学有限公司。保留所有权利。
The timecourse and scalp topography of interactions between neural responses to stimuli in different visual quadrants, straddling either the vertical or horizontal meridian, were studied in 15 subjects. Visual evoked potentials (VEPs) were recorded From 64 electrodes during a simple reaction time (RT) task. VEPs to single stimuli displayed in different quadrants were summed ('sum') and compared to the VEP response from simultaneous stimulation of the same two quadrants ('pair'). These responses would be equivalent if the neural responses to the single stimuli were independent. Divergence between the 'pair' and 'sum' VEPs indicates a neural response interaction. In each visual field. interactions occurred within 72-86 ms post-stimulus over parieto-occipital brain regions. Independent of visual quadrant, RTs were faster for stimulus pairs than single stimuli. This replicates the redundant target effect (RTE) observed for bilateral stimulus pairs and generalizes the RTE to unilateral stimulus pairs. Using Miller's 'race model inequality (Miller J. Divided attention: evidence for coactivation with redundant signals, Cognitive Psychology 1982:14:247-79), we found that probability summation could fully account for the RTE in each visual field. Although measurements from voltage waveforms replicated the observation of earlier peak P1 latencies for the 'pair' versus 'sum comparison (Miniussi C, Girelli M, Marzi CA. Neural site of the redundant target effect: electrophysiological evidence. Journal of Cognitive Neuroscience 1998,10:216-30), this did not hold with measurements taken from second derivative (scalp current density) waveforms. Since interaction effects for bilateral stimulus pairs occurred within 86 ms and require interhemispheric transfer. transcallosal volleys must arrive within 86 ms, which is earlier than previously calculated. Interaction effects for bilateral conditions were delayed by approximate to 10 ms versus unilateral conditions. consistent with current estimates of interhemispheric transmission time. Interaction effects place an upper limit on the lime required for neuronal ensembles to combine inputs from different quadrants of visual space ( approximate to 72 ms for unilateral and approximate to 82 ms for bilateral conditions). (C) 2001 Elsevier Science Ltd. All rights reserved.