DENDRITIC MORPHOLOGY AND AXON COLLATERALS OF CORTICOTECTAL, CORTICOPONTINE, AND CALLOSAL NEURONS IN LAYER-V OF PRIMARY VISUAL-CORTEX OF THE HOODED RAT
DENDRITIC MORPHOLOGY AND AXON COLLATERALS OF CORTICOTECTAL, CORTICOPONTINE, AND CALLOSAL NEURONS IN LAYER-V OF PRIMARY VISUAL-CORTEX OF THE HOODED RAT
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DOI：
10.1002/cne.902720111
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发表时间：
1988-06-01
影响因子：
2.5
通讯作者：
LIN, CS
中科院分区：
文献类型：
--
作者：
HALLMAN, LE;SCHOFIELD, BR;LIN, CS
最近的证据表明，皮质顶盖神经元属于只有一个的三个形态类的锥体细胞在第五层。本研究比较了树突状形态和轴突侧支的皮质顶盖，皮质桥，和第五层胼胝体神经元通过使用技术的基础上的辣根过氧化物酶和荧光染料的逆行运输，以及在体外细胞内染料注射。我们的结果表明，皮质顶盖和皮质桥脑神经元主要位于中上部的第V层。这些神经元具有中到大型的胞体，具有5或6个初级基底树突和一个顶树突上升到第I层。大约60%的这些细胞将轴突侧支输送到上级丘和脑桥。相反，胼胝体神经元形成异质组。一般细胞体小，呈锥体或卵圆形，可产生3 ~ 4个初级基树突。许多细胞具有分叉的顶端树突，并终止于第V层或第IV层。我们发现，胼胝体神经元不发送轴突侧支无论是上级丘或脑桥。我们的结论是，皮质顶盖和皮质桥脑系统是相似的intralaminar分布，树突状形态，和模式的轴突侧支，而胼胝体系统在这些特点不同。
Recent evidence indicates that corticotectal neurons belong to only one of the three morphological classes of pyramidal cells in layer V. The present study compares the dendritic morphology and axon collaterals of corticotectal, corticopontine, and layer V callosal neurons by using techniques based on the retrograde transport of horseradish peroxidase and fluorescent dyes as well as in vitro intracellular dye injections. Our results indicate that corticotectal and corticopontine neurons are located predominantly in the upper middle part of layer V. These neurons have medium to large somas with 5 or 6 primary basal dendrites and a single apical dendrite ascending to layer I. Approximately 60% of these cells send axon collaterals to both the superior colliculus and the pons. In contrast, callosal neurons form a heterogeneous group. In general, they hve small pyramidal or ovoid cell bodies which give rise to 3 or 4 primary basal dendrites. Many cells have an apical dendrite that bifurcates and terminates in layer V or IV. We find that callosal neurons do not send an axon collateral to either the superior colliculus or the pons. We conclude that the corticotectal and corticopontine systems are similar in their intralaminar distribution, dendritic morphology, and pattern of axon collaterals, whereas the callosal system differs in these characteristics.