Progress toward optimization of cryosurgery
Progress toward optimization of cryosurgery
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DOI：
10.1177/153303460400300202
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发表时间：
2004-04-01
影响因子：
2.8
通讯作者：
Gage, AA
中科院分区：
文献类型：
--
作者：
Baust, JG;Gage, AA
近年来，冷冻手术在各种肿瘤性和非肿瘤性疾病中的适用性已经扩大，特别是自从术中超声成为监测组织冷冻过程的方法以来。然而，疾病的持久性后，大概足够的冷冻外科治疗已披露的技术缺陷，可能是由于错误的应用程序的冻融循环或由于成像方法的缺点。显然，冷冻外科技术并不是最佳的，本文综述了组织冷冻的最佳剂量学、成像技术的最新进展以及对连续治疗的需求，并对提高冷冻外科疗效的进展进行了评估。
Cryosurgery for diverse neoplastic and non-neoplastic diseases has expanded in applicability in recent years, especially since intraoperative ultrasound became available as a method of monitoring the process of tissue freezing. However, persistence of disease after presumably adequate cryosurgical treatment has disclosed deficiencies in the technique, perhaps due to faulty application of the freeze-thaw cycles or due to shortcomings in the imaging method. Clearly cryosurgical technique is less than optimal.The optimal dosimetry for tissue freezing, the recent improvements in imaging techniques and the need for adjunctive therapy are defined in this review, which assesses the progress toward improving the efficacy of cryosurgery.