Rates of plasma porphyrin disappearance in fluorescent vs. red incandescent light exposure.
Rates of plasma porphyrin disappearance in fluorescent vs. red incandescent light exposure.
复制标题
荧光灯与红色白炽光照射下的血浆卟啉消失率。
DOI：
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发表时间：
1977
影响因子：
6.5
通讯作者：
V. Deleo
中科院分区：
文献类型：
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作者：
M. Poh;V. Deleo
在暴露于标准荧光室照明期间，评估血浆样本中的卟啉消失率。在这些条件下，红细胞生成性原卟啉患者标本中的原卟啉半衰期似乎不到30分钟。迟发性皮肤卟啉症患者血浆中的尿卟啉-共比例卟啉混合物更具光稳定性，半衰期可用小时来测量。所有的血浆卟啉可以通过在普通的红灯照明下进行所有的抽血、加工和分析程序，以及通过在黑暗中储存，在几天内防止类似的光降解。
The rates of porphyrin disappearance in plasma specimens were assessed during exposure to standard fluorescent room lighting. Protoporphyrin half-life in specimens from patients with erythropoietic protoporphyria appeared to be less than 30 min under these conditions. Uroporphyrin-coproporphyrin mixtures in plasmas of patients with porphyria cutanea tarda were more photostable, with half-lives measurable in terms of hours. All plasma porphyrins could be protected for several days from similar photodegradation by performing all blood drawing, processing, and assay procedures under ordinary red-incandescent illumination, and by storage in the dark.