Epidemiology and clinical characteristics of traumatic brain injury in Lebanon: A systematic review.
Epidemiology and clinical characteristics of traumatic brain injury in Lebanon: A systematic review.
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DOI：
10.1097/md.0000000000005342
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发表时间：
2016-11
期刊：
影响因子：
1.6
通讯作者：
Kobeissy F
中科院分区：
文献类型：
--
作者：
Abou-Abbass H;Bahmad H;Ghandour H;Fares J;Wazzi-Mkahal R;Yacoub B;Darwish H;Mondello S;Harati H;El Sayed MJ;Tamim H;Kobeissy F
创伤性脑损伤（TBI）是一种使人衰弱的医疗和新出现的公共卫生问题，由于多种因素，包括国内和与战争有关的行为，它正在影响全世界的人们。本文的目的是系统地审查黎巴嫩的创伤性脑损伤状况——黎巴嫩是一个中东国家，其卫生系统薄弱，受到几次战争和间歇性暴力爆发的影响——以便确定目前在知识方面的差距，指导未来的研究举措，并协助决策者规划进步和康复政策。最后于2016年4月15日检索OVID/Medline、PubMed、Scopus和谷歌Scholar数据库，以确定黎巴嫩所有已发表的TBI研究。以英语、阿拉伯语或法语发表的评估黎巴嫩TBI患者的研究值得纳入本综述。病例报告、综述、传记和摘要被排除在外。在整个审查过程中，审稿人在研究选择、数据提取和方法评估中使用Downs和Black检查表进行独立和重复的工作。总共有11项研究被认为是合格的，因为它们评估了黎巴嫩土壤上受创伤性脑损伤折磨的黎巴嫩患者。在确定的研究中发现了相当大的方法差异。除了两项评估家庭原因（如跌倒）的研究外，所有研究都报告了由战争相关伤害引起的创伤性脑损伤。脑外伤患者年龄分布呈现18 ~ 40岁青壮年和60岁以上老年人两个高峰，男性居多。只有三项研究报告了轻度创伤性脑损伤的发生率。死亡率、康复率和全身损伤率很少报道，所涉及的并发症也很少报道；感染是个例外。显然，黎巴嫩的创伤性脑损伤状况存在若干差距，需要通过今后在这一领域开展更多的基础、流行病学、临床和转译研究来弥补这些差距。
Supplemental Digital Content is available in the text Traumatic brain injury (TBI) is a debilitating medical and emerging public health problem that is affecting people worldwide due to a multitude of factors including both domestic and war-related acts. The objective of this paper is to systematically review the status of TBI in Lebanon – a Middle Eastern country with a weak health system that was chartered by several wars and intermittent outbursts of violence - in order to identify the present gaps in knowledge, direct future research initiatives and to assist policy makers in planning progressive and rehabilitative policies. OVID/Medline, PubMed, Scopus databases and Google Scholar were lastly searched on April 15th, 2016 to identify all published research studies on TBI in Lebanon. Studies published in English, Arabic or French that assessed Lebanese patients afflicted by TBI in Lebanon were warranting inclusion in this review. Case reports, reviews, biographies and abstracts were excluded. Throughout the whole review process, reviewers worked independently and in duplicate during study selection, data abstraction and methodological assessment using the Downs and Black Checklist. In total, 11 studies were recognized eligible as they assessed Lebanese patients afflicted by TBI on Lebanese soils. Considerable methodological variation was found among the identified studies. All studies, except for two that evaluated domestic causes such as falls, reported TBI due to war-related injuries. Age distribution of TBI victims revealed two peaks, young adults between 18 and 40 years, and older adults aged 60 years and above, where males constituted the majority. Only three studies reported rates of mild TBI. Mortality, rehabilitation and systemic injury rates were rarely reported and so were the complications involved; infections were an exception. Apparently, status of TBI in Lebanon suffers from several gaps which need to be bridged through implementing more basic, epidemiological, clinical and translational research in this field in the future.