ANTI-RO (SS-A) AND ANTI-LA (SS-B) IN PATIENTS WITH SJOGRENS-SYNDROME
ANTI-RO (SS-A) AND ANTI-LA (SS-B) IN PATIENTS WITH SJOGRENS-SYNDROME
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DOI：
10.1002/art.1780290207
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发表时间：
1986-02-01
影响因子：
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通讯作者：
ARNETT, FC
中科院分区：
文献类型：
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作者：
HARLEY, JB;ALEXANDER, EL;ARNETT, FC
Sjiigrm综合征患者的临床、血清学和遗传学结果与新开发的、灵敏的固相测定法的抗Ro （SS-A）、La （SS-B）和nRNP （Sm）抗体的定量测定相关。在86例干燥综合征患者血清中，超过96%的患者血清中含有抗ro (SS-A)， 87%的患者血清中含有抗la (SS-B)，其自身抗体浓度范围为4.8个loglo，而只有95%的患者血清中含有抗nrnp （Sm）。低水平的抗ro （SS-A）和抗la （SS-B）在10%和
Clinical, serologic, and genetic findings in Sjiigrm’s syndrome patients were correlated with quantitative determinations for antibody against Ro (SS-A), La (SS-B), and nRNP (Sm) using newly developed, sensitive solid-phase assays. In 86 Sjogren’s syndrome patient sera, more than 96% had anti-Ro (SS-A), and 87% had anti-La (SS-B), spanning a 4.8 loglo range of autoantibody concentration, whereas only 95% of the patients had anti-nRNP (Sm). Low levels of anti-Ro (SS-A) and anti-La (SS-B) were found in 10% and