Impact of stressful life events, depression, social support, coping, and cortisol on progression to AIDS
Impact of stressful life events, depression, social support, coping, and cortisol on progression to AIDS
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DOI：
10.1176/appi.ajp.157.8.1221
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发表时间：
2000-08-01
影响因子：
17.7
通讯作者：
Evans, DL
中科院分区：
文献类型：
--
作者：
Leserman, J;Petitto, JM;Evans, DL
目的：本研究前瞻性地研究了应激事件、抑郁症状、社会支持、应对方式和皮质醇水平对HIV-1感染进展的影响。方法：对82名没有艾滋病或症状的同性恋男性进行为期长达7.5年的每6个月的研究。男性是从北卡罗来纳州的农村和城市地区招募的，没有人在入境时使用抗逆转录病毒药物。疾病进展定义为CD4(+)淋巴细胞计数
Objective: This study examined prospectively the effects of stressful events, depressive symptoms, social support, coping methods, and cortisol levels on progression of HIV-1 infection.Method: Eighty-two homosexual men with HIV type-1 infection without AIDS or symptoms at baseline were studied every 6 months for up to 7.5 years. Men were recruited from rural and urban areas in North Carolina, and none was using antiretroviral medications at entry. Disease progression was defined as CD4(+) lymphocyte count