IMGT® databases, web resources and tools for immunoglobulin and T cell receptor sequence analysis, http//imgt.cines.fr
IMGT® databases, web resources and tools for immunoglobulin and T cell receptor sequence analysis, http//imgt.cines.fr
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DOI：
10.1038/sj.leu.2402637
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发表时间：
2003-01-01
期刊：
影响因子：
11.4
通讯作者：
Lefranc, MP
中科院分区：
文献类型：
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作者：
Lefranc, MP
IMGT，国际ImmMunoGeneTics数据库（（R））（http：imgt.cines.fr），是一个高质量的综合信息系统，专门研究人类和其他脊椎动物的免疫球蛋白（IG）、T细胞受体（TR）和主要组织相容性复合体（MHC），由LIGM于1989年在法国蒙彼利埃第二大学CNRS创建。IMGT提供了对标准化数据的通用访问，这些数据包括核苷酸和蛋白质序列、寡核苷酸引物、基因图谱、遗传多态性、特异性、2D和3D结构。IMGT包括几个数据库（IMGT/LIGM-DB，IMGT/3Dstructure-DB，IMGT/HLA-DB），网络资源（“IMGT Marie-Paule页面”）和交互式工具（IMGTN-OUEST，IMGT/JunctionAnalysis）。本文描述的IMGT专业注释的数据和工具对于分析白血病、淋巴瘤和骨髓瘤以及涉及抗原受体基因座的易位中的IG和TR重排特别有用。IMGT可在http://imgt.cines.fr上免费获得。
IMGT, the international ImMunoGeneTics database((R)) (http://imgt.cines.fr), is a high-quality integrated information system specializing in immunoglobulins (IG), T cell receptors (TR) and major histocompatibility complex (MHC) of human and other vertebrates, created in 1989, by LIGM, at the Universite Montpellier II, CNRS, Montpellier, France. IMGT provides a common access to standardized data which include nucleotide and protein sequences, oligonucleotide primers, gene maps, genetic polymorphisms, specificities, 2D and 3D structures. IMGT includes several databases (IMGT/LIGM-DB, IMGT/3Dstructure-DB, IMGT/HLA-DB), Web resources ('IMGT Marie-Paule page') and interactive tools (IMGTN-OUEST, IMGT/JunctionAnalysis). IMGT expertly annotated data and tools described in this paper are particularly useful for the analysis of the IG and TR rearrangements in leukemia, lymphoma and myeloma, and in translocations involving the antigen receptor loci. IMGT is freely available at http://imgt.cines.fr.