Rheological behaviour and mechanical characterization of injectable poly(propylene fumarate)/single-walled carbon nanotube composites for bone tissue engineering
Rheological behaviour and mechanical characterization of injectable poly(propylene fumarate)/single-walled carbon nanotube composites for bone tissue engineering
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DOI：
10.1088/0957-4484/16/7/030
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发表时间：
2005-07-01
期刊：
影响因子：
3.5
通讯作者：
Mikos, AG
中科院分区：
文献类型：
--
作者：
Shi, XF;Hudson, JL;Mikos, AG
本研究研究了表面活性剂的使用或单壁碳纳米管的功能化对其在非交联富马酸聚丙烯（PPF）中的分散的影响，以及交联复合材料的机械增强与单壁碳纳米管浓度的关系。流变学测量表明，在低浓度0.05 wt%的未交联PPF中，SWNT具有良好的分散性，在所有测试配方中，高浓度的SWNT聚集。力学测试表明，交联纳米复合材料的压缩和弯曲力学性能显著增强，在0.05 wt%量级的低SWNT浓度下达到峰值。例如，在0.05 wt%的载荷下，功能化swnt纳米复合材料的压缩模量增加了74%，弯曲模量增加了69%。然而，这种增强与表面活性剂的使用或测试的单壁碳纳米管的功能化无关。扫描电子显微镜对断裂的纳米复合材料表面进行检查，发现在较高浓度下形成了SWNT聚集体，证实了流变学和力学数据。这些结果表明，单个单壁碳纳米管在非交联配方中的分散对于骨组织工程应用的可注射纳米复合材料的开发至关重要。
This work investigated the effects of the use of a surfactant or the functionalization of single-walled carbon nanotubes (SWNTs) on their dispersion in uncrosslinked poly(propylene fumarate) (PPF) and the mechanical reinforcement of crosslinked composites as a function of the SWNT concentration. Rheological measurements showed good dispersion of SWNTs in uncrosslinked PPF at low concentrations of 0.05 wt% and SWNT aggregation for higher concentrations for all formulations examined. Mechanical testing demonstrated significant reinforcement in the compressive and flexural mechanical properties of crosslinked nanocomposites which peaked for low SWNT concentrations of the order of 0.05 wt%. For example, a 74% increase was recorded for the compressive modulus and a 69% increase for the flexural modulus of nanocomposites with functionalized SWNTs at a 0.05 wt% loading. Nevertheless, this reinforcement was not related to the use of a surfactant or the functionalization of the SWNTs tested. Scanning electron microscopy examinations of fractured nanocomposite surfaces revealed the formation of SWNT aggregates at higher concentrations corroborating the rheological and mechanical data. These results suggest that the dispersion of individual SWNTs in a uncrosslinked formulation is pivotal to the development of injectable nanocomposites for bone tissue engineering applications.