Personal digital assistants used to document compliance of bacterial vaginosis treatment
Personal digital assistants used to document compliance of bacterial vaginosis treatment
复制标题
DOI：
10.1097/01.olq.0000135990.21755.51
复制
发表时间：
2004-08-01
影响因子：
3.1
通讯作者：
Lambert, J
中科院分区：
文献类型：
--
作者：
Bartley, JB;Ferris, DG;Lambert, J
目的：本研究的目的是估计患者的依从性与口服和阴道甲硝唑治疗细菌性阴道病使用个人数字助理（PDA）和纸质diaries.Goal：本研究的目的是评估一种新的依从性documentation approach.Study：每次剂量的阴道内或口服甲硝唑后，71名受试者记录的时间在纸上日记和回答PDA上的问题。所有PDA输入都在不知不觉中打上了时间和日期戳。受试者返回接受2周和6周治疗后检查。使用重复测量多变量方差分析（ANOVA）计算依从性。结果：口服甲硝唑组的平均患者依从率与纸日记相比PDA（分别为68.3%和50.0%，P = 0.001）更大。观察到PDA与纸质日记的依从性一致率为69.0%（kappa = 0.4）。大多数不合规的受试者报告说，他们符合PDA和纸质diary.Conclusions：PDA可以更准确地记录真正的遵守率，可以合理的工具，以评估遵守阴道内抗菌药物或避孕试验。
Objective: The objective or this study was to estimate patient compliance with oral and vaginal metronidazole treatment of bacterial vaginosis using personal digital assistants (PDAs) and paper diaries.Goal: The goal of this study was to assess a novel compliance documentation approach.Study: After each dose of intravaginal or oral metronidazole, 71 subjects recorded the time on a paper diary and answered questions on a PDA. All PDA entries were unknowingly time-date-stamped. Subjects returned for 2- and 6-week posttreatment examinations. Compliance was calculated using a repeated-measures multivariate analysis of variance (ANOVA).Results: Mean patient compliance rates within the oral metronidazole group were greater with the paper diary compared with the PDA (68.3% and 50.0%, respectively, P = 0.001). The observed rate of compliance agreement for PDA versus paper diary was 69.0% (kappa = 0.4). The majority of noncompliant subjects reported they were compliant with the PDA and paper diary.Conclusions: PDAs could more accurately document true compliance rates and could be reasonable instruments to assess compliance in intravaginal antimicrobial drug or contraceptive trials.