Imaging the mechanics and electromechanics of the heart.
Imaging the mechanics and electromechanics of the heart.
复制标题
心脏的力学和机电成像。
DOI：
10.1109/iembs.2006.260911
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Pernot,Mathieu
中科院分区：
文献类型：
--
作者：
Konofagou,ElisaE;Fung-Kee-Fung,Simon;Luo,Jianwen;Pernot,Mathieu
心脏是一个由电力驱动的机械泵。我们以前已经证明，心肌的收缩性可以可靠地用于评估缺血程度，使用心肌弹性成像。心肌弹性成像使用超声心动图上的信号处理技术来估计心肌自然收缩期间的位移和应变，以便评估由于疾病而导致的机械特性的变化。在本文中，我们表明，弹性成像技术可用于估计和成像的力学和电动力学的正常和病理心脏在体内。为了在整个心动周期中对力学进行成像，最小帧速率被确定为在长轴视图中大约为150 fps，在短轴视图中大约为300 fps。测量增量和累积位移和应变，并成像以表征正常功能和与梗死心肌的区分。为了对机电功能进行成像，在犬和人的收缩末期期间，对连续心动周期中的增量位移进行成像。正常犬的收缩波速度比正常人高两倍，比缺血犬低两倍。总之，我们已经证明，弹性成像技术可用于检测和量化的力学和电动力学的心肌在体内。正在进行的研究需要评估心肌弹性成像在体内表征和量化缺血和梗死。
The heart is a mechanical pump that is electrically driven. We have previously shown that the contractility of the cardiac muscle can reliably be used in order to assess the extent of ischemia using myocardial elastography. Myocardial elastography estimates displacement and strain during the natural contraction of the myocardium using signal processing techniques on echocardiograms in order to assess the change in mechanical properties as a result of disease. In this paper, we showed that elastographic techniques can be used to estimate and image both the mechanics and electromechanics of normal and pathological hearts in vivo. In order to image the mechanics throughout the entire cardiac cycle, the minimum frame rate was determined to be on the order of 150 fps in a long-axis view and 300 fps in a short-axis view. The incremental and cumulative displacement and strains were measured and imaged for the characterization of normal function and differentiation from infracted myocardium. In order to image the electromechanical function, the incremental displacement was imaged in consecutive cardiac cycles during end-systole in both dogs and humans. The contraction wave velocity in normal dogs was found to be twice higher than in normal humans and twice lower than in ischemic dogs. In conclusion, we have demonstrated that elastographic techniques can be used to detect and quantify the mechanics and electromechanics of the myocardium in vivo. Ongoing investigations entail assessment of myocardial elastography in characterizing and quantifying ischemia and infarction in vivo.