Ocular Vestibular Evoked Myogenic Potentials in Response to Air-Conducted Sound and Bone-Conducted Vibration in Vestibular Schwannoma
Ocular Vestibular Evoked Myogenic Potentials in Response to Air-Conducted Sound and Bone-Conducted Vibration in Vestibular Schwannoma
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DOI：
10.1097/mao.0b013e31828d6539
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发表时间：
2013-09-01
影响因子：
2.1
通讯作者：
Yamasoba, Tatsuya
中科院分区：
文献类型：
--
作者：
Kinoshita, Makoto;Iwasaki, Shinichi;Yamasoba, Tatsuya
目的：为了阐明眼前庭诱发肌源性电位（oVEMPs）到气导声（ACS）的起源和途径，我们比较了oVEMPs与ACS、oVEMPs与骨导振动（BCV）、颈VEMPs（cVEMPs）与ACS以及单侧前庭神经鞘瘤（VS）患者冷热试验的结果。45例未经治疗的单侧VS患者。主要结果测量：每位患者接受前庭试验，包括oVEMPs至ACS，oVEMPs至BCV，cVEMPs至ACS和热量试验。结果：在45例患者中，28例患者（63%）仅在患侧显示ACS的oVEMPs减少或缺失。oVEMPs对ACS、oVEMPs对BCV、cVEMPs对ACS或热量试验的异常反应率无显著差异。oVEMPs对ACS的反应与oVEMPs对BCV的反应及冷热试验结果有显著相关性（p < 0.05），而与cVEMPs对ACS的反应无显著相关性（p < 0.05）。结论：oVEMPs对ACS的反应主要由上级前庭神经介导，可能反映了椭圆囊的功能。
Objective: To clarify the origin and pathways of ocular vestibular evoked myogenic potentials (oVEMPs) to air-conducted sound (ACS), we compared the results of oVEMPs with ACS, with oVEMPs with bone-conducted vibration (BCV), cervical VEMPs (cVEMPs) with ACS, and the caloric test in patients with unilateral vestibular schwannoma (VS).Study Design: Retrospective review.Setting: Tertiary referral center.Patients: Forty-five patients with untreated unilateral VS.Main Outcome Measure: Each patient underwent vestibular tests, including oVEMPs to ACS, oVEMPs to BCV, cVEMPs to ACS, and caloric tests. The correlations among these tests were evaluated.Results: Of the 45 patients recruited, 28 patients (63%) showed reduced or absent oVEMPs to ACS solely on the affected side. There were no significant differences in abnormal response ratios among oVEMPs to ACS, oVEMPs to BCV, cVEMPs to ACS, or the caloric test. The results of oVEMPs to ACS had a significant correlation with those of oVEMPs to BCV and the caloric test (p < 0.05) but not with those of cVEMPs to ACS (p < 0.05).Conclusion: These findings support the hypothesis that oVEMP in response to ACS are predominantly mediated by the superior vestibular nerve and probably reflect the function of the utricle.