Cancer Risk and Behavioral Factors, Comorbidities, and Functional Status in the US Elderly Population.
Cancer Risk and Behavioral Factors, Comorbidities, and Functional Status in the US Elderly Population.
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DOI：
10.5402/2011/415790
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发表时间：
2011-01-01
期刊：
影响因子：
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通讯作者：
Yashin, Anatoliy
中科院分区：
文献类型：
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作者：
Akushevich, Igor;Kravchenko, Julia;Yashin, Anatoliy
大约80%的癌症是在老年人中诊断出来的，高达75%的癌症与行为因素有关。提出了一种估计各种可测量因素（包括行为/生活方式）对美国老年人群癌症风险的贡献的方法。具有全国代表性的国家长期护理调查（NLTCS）数据用于测量美国老年人群（65岁以上）的功能状态和行为因素，与NLTCS中每个人相关的医疗保险索赔文件用于估计癌症发病率。协会（即，对乳腺癌、前列腺癌、肺癌和结肠癌的危险因素进行了评价和讨论。行为风险因素显著影响美国老年人的癌症风险。最有影响力的潜在可预防的风险因素可以使用NLTCS-Medicare链接数据集通过这种方法检测，并使用具有详细风险因素描述的其他数据集进行进一步深入分析。
About 80% of all cancers are diagnosed in the elderly and up to 75% of cancers are associated with behavioral factors. An approach to estimate the contribution of various measurable factors, including behavior/lifestyle, to cancer risk in the US elderly population is presented. The nationally representative National Long-Term Care Survey (NLTCS) data were used for measuring functional status and behavioral factors in the US elderly population (65+), and Medicare Claims files linked to each person from the NLTCS were used for estimating cancer incidence. The associations (i.e., relative risks) of selected factors with risks of breast, prostate, lung and colon cancers were evaluated and discussed. Behavioral risk factors significantly affected cancer risks in the US elderly. The most influential of potentially preventable risk factors can be detected with this approach using NLTCS-Medicare linked dataset and for further deeper analyses employing other datasets with detailed risk factors description.