Massage timing affects postexercise muscle recovery and inflammation in a rabbit model.
Massage timing affects postexercise muscle recovery and inflammation in a rabbit model.
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DOI：
10.1249/mss.0b013e31827fdf18
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发表时间：
2013-06
影响因子：
4.1
通讯作者：
Best TM
中科院分区：
文献类型：
--
作者：
Haas C;Butterfield TA;Abshire S;Zhao Y;Zhang X;Jarjoura D;Best TM
本研究比较了离心运动（EEX）后即刻与延迟按摩样压缩负荷（MLL）对峰值等长扭矩恢复和炎性细胞浸润的影响。18只成年新西兰白色兔用腓神经袖套刺激后肢胫前肌。在一次EEX后，将家兔随机分配至MLL方案（0.5 Hz，10 N，15 min），在EEX后立即开始，在ESX后48小时开始，或无MLL对照，并连续进行4天。获得了EEX前后以及连续4天MLL或无MLL后21个关节角的扭矩-角度（T-Θ）关系。在最终处理后获得肌肉湿重和免疫组织化学切片。EEX使峰值等长扭矩输出平均降低51%（±13%）。最大峰值扭矩恢复发生在立即应用MLL时。即刻和延迟MLL（p=0.0012）、即刻MLL和对照（p<0.0001）以及延迟MLL和对照（p=0.025）之间的扭矩恢复存在差异。免疫组织化学分析显示，即刻（p=0.71）和延迟MLL（p=0.12）之间RPN 3/57和CD 11b阳性细胞数量的差异为39.3%和366.0%。与对照相比，T-Θ曲线下面积显示即刻（p<0.0001）和延迟（p=0.0051）MLL的差异。运动产生了平均10°± 0.2 °的运动前峰值等长扭矩角偏移。对照组、即刻MLL组和延迟MLL组与运动后角度相比产生了平均1/4的角度偏移（分别为p=0.28、p=0.03和p=0.47）。EEX后，即刻MLL在恢复肌肉功能和调节炎性细胞浸润方面比延迟MLL更有益。这些发现邀请类似的人类研究，以便对基于按摩的疗法的最佳时机做出明确的结论。
This study compared the effect of immediate versus delayed massage-like compressive loading (MLL) on peak isometric torque recovery and inflammatory cell infiltration following eccentric exercise (EEX). Eighteen skeletally mature New Zealand White rabbits were instrumented with peroneal nerve cuffs for stimulation of hindlimb tibialis anterior muscles. Following a bout of EEX, rabbits were randomly assigned to a MLL protocol (0.5Hz, 10N, 15min) started immediately post-EEX, 48 hours post-EXX, or no-MLL control and performed for four consecutive days. A torque-angle (T-Θ) relationship was obtained for 21 joint angles pre and post-EEX and post four consecutive days of MLL or no-MLL. Muscle wet weights and immunohistochemical sections were obtained following final treatments. EEX produced an average 51% (±13%) decrease in peak isometric torque output. Greatest peak torque recovery occurred with immediate application of MLL. There were differences in torque recovery between immediate and delayed MLL (p=0.0012), immediate MLL and control (p<0.0001), and delayed MLL and control (p=0.025). Immunohistochemical analysis showed 39.3% and 366.0% differences in the number of RPN3/57 and CD11b positive cells between immediate (p=0.71) and delayed MLL (p=0.12). Area under the T-Θ curve showed a difference for immediate (p<0.0001) and delayed (p=0.0051) MLL as compared to control. Exercise produced an average 10°± 0.2 rightward shift from pre exercise peak isometric torque angle. Control, immediate MLL and delayed MLL produced an average leftward angular shift from the post exercise angle (p=0.28, p=0.03, and p=0.47, respectively). Post-EEX, immediate MLL was more beneficial than delayed MLL in restoring muscle function and modulating inflammatory cell infiltration. These findings invite similar human studies in order to make definitive conclusions on optimal timing of massage-based therapies.