ARGININE VASOPRESSIN AND THE RENAL RESPONSE TO WATER LOADING IN CONGESTIVE-HEART-FAILURE
ARGININE VASOPRESSIN AND THE RENAL RESPONSE TO WATER LOADING IN CONGESTIVE-HEART-FAILURE
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DOI：
10.1016/0002-9149(86)90065-2
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发表时间：
1986-08-01
影响因子：
2.8
通讯作者：
COWLEY, AW
中科院分区：
文献类型：
--
作者：
GOLDSMITH, SR;FRANCIS, GS;COWLEY, AW
先前的研究表明，在单独比较的基础上，CHF患者的血浆精氨酸加压素（APV）水平在给定的血清渗透压下不适当地升高。为进一步探讨CHF患者血浆AVP的动态调节，我们比较了26例CHF患者和14例正常人血浆AVP对15 ~ 20 ml/kg饮水负荷的反应。在正常受试者中，血清渗透压从289 . ±. 5.0至282 .+-。5.0 mOsm/kg（p
Previous studies have shown on the basis of isolated comparisons that plasma arginine vasopressin (APV) levels are inappropriately increased for a given serum osmolality in patients with CHF. To explore further the osmoregulation of AVP in this condition, the response of plasma AVP to a 15- to 20-ml/kg oral water load was compared in 26 patients with CHF and 14 normal subjects. In the normal subjects, serum osmolality decreased from 289 .+-. 5.0 to 282 .+-. 5.0 mOsm/kg (p