Determination of blood pressure percentiles in normal-weight children: Some methodological issues
Determination of blood pressure percentiles in normal-weight children: Some methodological issues
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DOI：
10.1093/aje/kwm348
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发表时间：
2008-03-15
影响因子：
5
通讯作者：
Falkner, B.
中科院分区：
文献类型：
--
作者：
Rosner, B.;Cook, N.;Falkner, B.
儿童血压一直与成人血压相关，这对心血管疾病的长期预防具有重要意义。儿童肥胖症的流行导致儿童血压相应增加。在这篇论文中，作者利用国家高血压教育计划儿童和青少年高血压工作组(儿科特别工作组)数据库中49,967名儿童的数据，建立了正常体重儿童儿童血压的正常值(根据疾病控制和预防中心的指南，体重指数和第85百分位数)作为年龄、性别和身高的函数。作者考虑了三种类型的儿童血压数据模型，包括多项式回归、限制三次样条法和分位数回归，后者提供了最好的拟合。本文提出的性别标准是年龄和身高的非线性函数，通常略低于以前根据儿科工作队数据制定的标准，包括正常体重和超重儿童。
Blood pressure in children has consistently been related to adult blood pressure, with implications for long-term prevention of cardiovascular disease. The epidemic of obesity in children has resulted in corresponding increases in childhood blood pressure. In this paper, the authors develop norms for childhood blood pressure among normal-weight children (body mass index < 85th percentile based on Centers for Disease Control and Prevention guidelines) as a function of age, sex, and height, using data from 49,967 children included in the database of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (the Pediatric Task Force). The authors considered three types of models for pediatric blood pressure data, including polynomial regression, restricted cubic splines, and quantile regression, with the latter providing the best fit. The sex-specific norms presented here are a nonlinear function of both age and height and are generally slightly lower than previously developed norms based on Pediatric Task Force data including both normal-weight and overweight children.