Mothers' Preferences and Willingness to Pay for Human Papillomavirus Vaccination for Their Daughters: A Discrete Choice Experiment in Hong Kong

Mothers' Preferences and Willingness to Pay for Human Papillomavirus Vaccination for Their Daughters: A Discrete Choice Experiment in Hong Kong
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母亲为女儿接种人乳头瘤病毒疫苗的偏好及支付意愿:一项在香港开展的离散选择实验

DOI:
10.1016/j.jval.2017.10.012
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发表时间:
2018-05-01
期刊:
影响因子:
4.5
通讯作者:
McGhee, Sarah M.
McGhee, Sarah M.
中科院分区:
医学2区
文献类型:
--
作者:
Wong, Carlos K. H.;Man, Kenneth K. C.;McGhee, Sarah M.

文献摘要

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目标:确定香港母亲对女儿接种人乳头瘤病毒(HPV)疫苗的偏好及其支付意愿(WTP)。方法:开发了具有两种选择研究设计的离散选择实验调查。数据从儿科专科门诊收集了 482 名女儿年龄在 8 至 17 岁之间的母亲。评估了 HPV 疫苗四个属性(预防宫颈癌、保护持续时间、副作用和自付费用)的偏好。使用多项逻辑回归估计边际和总体支付意愿。通过亚组分析探讨社会经济因素对母亲支付意愿的影响。结果:副作用、对宫颈癌的保护、保护期限和自付费用决定了接受或不接受疫苗的决定。所有属性对疫苗的偏好和支付意愿都有统计学上的显着影响。理想疫苗的最大支付意愿(即 100% 保护、终身保护期限和 0% 副作用)为 8976 港元(1129 美元)。目前可用疫苗的预计支付意愿为 1620 港元(208 美元),低于当前市场价格。在家庭月收入超过10万港元(12,821美元)的人群中,目前提供的疫苗的购买意愿高于市场价格。结论:这项研究通过确定母亲对理想或改进和当前疫苗技术的看法,提供了关于母亲如何看待和重视 HPV 疫苗特征的新数据。这些发现可有助于未来改进HPV疫苗的政策,并对香港的免疫服务有所帮助。
Objectives: To determine the preference of mothers in Hong Kong and their willingness to pay (WTP) for human papillomavirus (HPV) vaccination for their daughters. Method: A discrete choice experiment survey with a two-alternative study design was developed. Data were collected from pediatric specialist outpatient clinics from 482 mothers with daughters aged between 8 and 17 years. Preferences of the four attributes of HPV vaccines (protection against cervical cancer, protection duration, side effects, and out-of-pocket costs) were evaluated. The marginal and overall WTP were estimated using multinomial logistic regression. A subgroup analysis was conducted to explore the impact of socioeconomic factors on mothers' WTP. Results: Side effects, protection against cervical cancer, protection duration, and out-of-pocket cost determined the decision to receive or not receive the vaccine. All attributes had a statistically significant effect on the preference of and the WTP for the vaccine. Maximum WTP for ideal vaccines (i.e., 100% protection, lifetime protection duration, and 0% side effects) was HK$8976 (US $1129). The estimated WTP for vaccines currently available was HK$1620 (US $208), lower than the current market price. Among those who had a monthly household income of more than HK$100,000 (US $12,821), the WTP for vaccines currently offered was higher than the market price. Conclusions: This study provides new data on how features of the HPV vaccine are viewed and valued by mothers by determining their perception of ideal or improved and current vaccine technologies. These findings could contribute to future policies on the improvement of HPV vaccine and be useful for the immunization service in Hong Kong.