The role of anthropometric and nutritional factors on breast cancer risk in African-American women.
The role of anthropometric and nutritional factors on breast cancer risk in African-American women.
复制标题
DOI：
10.1017/s136898001100303x
复制
发表时间：
2012-04
影响因子：
3.2
通讯作者：
Bandera, Elisa V.
中科院分区：
文献类型：
--
作者：
Chandran, Urmila;Hirshfield, Kim M.;Bandera, Elisa V.
虽然营养、体力活动和体型对乳腺癌风险的作用已被广泛研究，但大多数研究都是在高加索人群中进行的。然而，在非裔美国人和高加索妇女之间，肿瘤生物学和这些因素的患病率存在众所周知的差异。本文的目的是进行审查的作用，饮食因素，人体测量学和体力活动对乳腺癌的风险在非洲裔美国妇女。本综述纳入了26篇研究文章，这些文章对非裔美国妇女的这些因素进行了风险估计，并纳入了5篇涉及非美国黑人妇女的文章。人体测量和营养因素对乳腺癌风险影响的种族差异非裔美国人和非美国黑人女性基于少数几项在非裔美国人女性中提出的研究结果，发现绝经前后非裔美国人女性与体力活动呈负相关，而人体测量和其他饮食因素（如酒精）的相关性尚不清楚。评估非裔美国妇女分子亚型影响的研究太少，样本量太小，无法提供明确的结论。某些营养和生活方式因素对非裔美国人乳腺癌的影响与在白色妇女中观察到的影响没有明显区别。然而，对这一少数群体进行进一步研究，以获得更多的验证性结果，这是一个巨大的需求。
While the role of nutrition, physical activity, and body size on breast cancer risk has been extensively investigated, most of these studies were conducted in Caucasian populations. However, there are well known differences in tumor biology and the prevalence of these factors between African American and Caucasian women. The objective of this paper was to conduct a review on the role of dietary factors, anthropometry, and physical activity on breast cancer risk in African American women. Twenty-six research articles that presented risk estimates on these factors in African American women and five articles involving non-US Black women were included in this review. Racial disparities in the impact of anthropometric and nutritional factors on breast cancer risk African American and non-US Black women Based on the few studies that presented findings in African American women, an inverse association with physical activity was found for pre and postmenopausal African American women, while the association for anthropometric and other dietary factors, such as alcohol, was unclear. Studies assessing the effect by molecular subtypes in African American women were too few and based on sample sizes too small to provide definitive conclusions. The effect of certain nutrition and lifestyle factors on breast cancer in African American is not starkly distinct from those observed in White women. However, there is an enormous need for further research on this minority group to obtain more confirmatory findings.