EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines)
EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines)
复制标题
DOI：
10.1016/j.eururo.2004.07.016
复制
发表时间：
2004-11-01
期刊：
影响因子：
23.4
通讯作者：
de la Rosette, JJMCH
中科院分区：
文献类型：
--
作者：
Madersbacher, S;Alivizatos, G;de la Rosette, JJMCH
目的：提供关于具有提示良性前列腺梗阻 (BPO) 的下尿路症状 (LUTS) 的男性评估、治疗和随访的 EAU 指南的首次更新。方法：根据 MEDLINE(R) 检索结果（集中于 1999-2003 年）进行系统文献综述。结合专家意见，对诊断测试、治疗选择和随访的有用性提出了建议。结果：在初步评估期间，建议进行以下测试：病史、体格检查（包括直肠指检）、国际前列腺症状评分、尿液分析、血清肌酐和前列腺特异性抗原测量、尿流率测定和排尿后残余量。所有其他测试都是可选的或不推荐的。治疗的目的是改善 LUTS 和生活质量，并预防严重的 BPE 相关并发症。 5α-还原酶 I 型和 II 型抑制剂的开发以及 MTOPS 试验的数据为联合疗法提供了科学证据，是自第一个版本以来最重要的创新。最后，对自然史的更详细的了解以及对进展的几个危险因素的识别是风险概况导向（预防）治疗的基础。结论：提出了 BPO 引起的 LUTS 患者的评估、治疗和随访的更新建议。 (C) 2004 Elsevier B.V. 保留所有权利。
Objective: To provide the first update of the EAU guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic obstruction (BPO).Methods: A systematic literature review was conducted based on the results of a MEDLINE(R) search concentrating on the years 1999-2003. In combination with expert opinions recommendations were made on the usefulness of diagnostic tests, therapeutic options and follow-up.Results: During initial assessment the following tests are recommended: medical history, physical examination including digital-rectal examination, International Prostate Symptom Score, urinalysis, serum creatinine and prostate specific antigen measurement, uroflowmetry and post-void residual volume. All other tests are optional or not recommended. Aim of treatment is to improve LUTS and quality of life and to prevent severe BPE-related complications. Development of a 5alpha-reductase type I and II inhibitor and the data of the MTOPS trial providing scientific evidence for a combination therapy were the most significant innovations since the first version. Finally a more detailed knowledge on the natural history with identification of several risk factors for progression is the basis for a risk-profile orientated (preventive) therapy.Conclusions: Updated recommendations for assessment, treatment, and follow-up of patients with LUTS due to BPO are presented. (C) 2004 Elsevier B.V. All rights reserved.