Computational Modelling of Magnetic Nanoparticle Properties and In Vivo Responses.
Computational Modelling of Magnetic Nanoparticle Properties and In Vivo Responses.
复制标题
磁性纳米颗粒特性和体内反应的计算模型。
DOI：
10.2174/0929867323666161018141902
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发表时间：
2017
影响因子：
4.1
通讯作者：
D. Winkler
中科院分区：
文献类型：
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作者：
D. Winkler
纳米粒子在医学和其他领域如光子学中有许多应用。磁性纳米颗粒在医学上比非磁性硬纳米颗粒具有额外的优势，因为它们的磁性使它们成为治疗中的热疗应用和敏感的诊断成像应用的理想选择。我回顾了有关纳米颗粒的磁特性的计算模型的文献。这种模型有可能加速用于医疗应用的磁性纳米颗粒的设计。目前的许多文献都涉及磁性纳米粒子的建模，用于诱导异常细胞的高热，大量的工作旨在模拟和预测医学成像和靶向药物和基因治疗的性质。
Nanoparticles are finding many applications in medicine and other fields like photonics. Magnetic nanoparticles have additional advantages in medicine over non-magnetic hard nanoparticles, as their magnetic properties make them ideal for hyperthermic applications in therapy and for sensitive diagnostic imaging applications. I review the literature on computational models of the magnetic properties of nanoparticles specifically. Such models have the potential to accelerate the design of magnetic nanoparticles for medical applications. Much of the current literature relates to the modelling of magnetic nanoparticles for inducing hyperthermia in aberrant cells, with significant bodies of work aimed at simulating and predicting properties for medical imaging and targeted delivery of drugs and gene therapies.