Association between symptoms of bilateral numbness and/or paresthesia in the feet and postural instability in Japanese patients with diabetes
Association between symptoms of bilateral numbness and/or paresthesia in the feet and postural instability in Japanese patients with diabetes
复制标题
日本糖尿病患者双足麻木和/或感觉异常症状与姿势不稳的关联
DOI：
10.1007/s13340-015-0214-2
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Miyamatsu N.
中科院分区：
文献类型：
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作者：
Morimoto A;Sonoda N;Ugi S;Morino K;Sekine O;Nemoto K;Ogita M; Tatsumi Y;Murata S;Maegawa H;Miyamatsu N.
目的本研究评估了日本糖尿病患者的双脚麻木和/或感觉异常症状与姿势不稳之间的关联。方法本横断面研究纳入了 303 名年龄 40-88 岁的糖尿病患者，他们于 2013 年 1 月至 7 月期间转诊至滋贺医科大学医院糖尿病门诊。姿势描记测试用于评估患者的姿势摇摆。姿势摇摆的指标是总长度和包络面积。根据是否存在足部双侧麻木和/或感觉异常症状，使用协方差分析来估计姿势摇摆指数的多变量调整平均值。结果在 303 名患者中，35 例 (11.6%) 出现双侧足部麻木和/或感觉异常症状。在调整年龄、性别、糖尿病视网膜病变、定期运动、体重指数、糖化血红蛋白水平和股四头肌力量后，有症状的患者在姿势描记测试中比无症状的患者具有更高的姿势摇摆长度和包络面积。此外，我们在分析 234 名年龄≥60 岁的患者时观察到了类似的结果。结论我们的研究结果表明，有双足麻木和/或感觉异常症状的患者可能比没有症状的患者有更多的姿势不稳定性。
AimThis study assessed the association between symptoms of bilateral numbness and/or paresthesia in the feet and postural instability in Japanese patients with diabetes.MethodsThis cross-sectional study included 303 patients with diabetes, aged 40–88 years, who were referred to an outpatient diabetic clinic between January and July 2013 at Shiga University of Medical Science Hospital. A posturography test was used to evaluate postural sway in patients. Indices of postural sway were the total length and the enveloped area. Analysis of covariance was used to estimate the multivariable-adjusted means of indices of postural sway according to the presence or absence of symptoms of bilateral numbness and/or paresthesia in the feet.ResultsOf 303 patients, 35 (11.6 %) had symptoms of bilateral numbness and/or paresthesia in the feet. After adjustment for age, sex, diabetic retinopathy, regular exercise, body mass index, hemoglobin A1c level, and quadriceps’ strength, patients with symptoms had higher levels of postural sway length and an enveloped area in the posturography test than those without symptoms. In addition, we observed similar results when we analyzed 234 patients aged ≥60 years.ConclusionsOur findings suggest that patients who had symptoms of bilateral numbness and/or paresthesia in the feet may have more postural instability than those without symptoms.