Computational approach to systems biology: From fraction to integration and beyond
Computational approach to systems biology: From fraction to integration and beyond
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DOI：
10.1109/tnb.2004.833699
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发表时间：
2004-09-01
影响因子：
3.9
通讯作者：
Mishra, SK
中科院分区：
文献类型：
--
作者：
Dhar, PK;Zhu, H;Mishra, SK
系统生物学是一种理解整个生物系统运作的方法。用于系统分析的各种方法从实验到计算都有。在本文中，我们描述了系统生物学的基本概念、建模挑战，这些挑战来自于生物系统中组件之间的大规模并行交互，以及超越模块化知识集成的东西。
Systems biology is an approach to understanding the workings of whole biological systems. The various methods used for systems analyses range from experimental to computational. In this paper, we describe basic concepts of systems biology, modeling challenges that arise from the massively parallel interaction among components in biological systems, and what lies beyond integration of modular knowledge.