Quantitative analysis of the choline acetyltransferase‐immunoreactive axonal network in the cat primary visual cortex: I. Adult cats
Quantitative analysis of the choline acetyltransferase‐immunoreactive axonal network in the cat primary visual cortex: I. Adult cats
复制标题
猫初级视觉皮层胆碱乙酰转移酶免疫反应性轴突网络的定量分析：I. 成年猫
DOI：
10.1002/cne.902580107
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发表时间：
1987
影响因子：
2.5
通讯作者：
W. Singer
中科院分区：
文献类型：
--
作者：
C. Stichel;W. Singer
用胆碱乙酰转移酶（ChAT）单克隆抗体免疫细胞化学方法，对成年猫视皮层胆碱能轴突的层状分布进行了定量分析。ChAT（+）纤维和静脉曲张在17区内的不同位置进行了计数，并在各种动物的分布模式进行了比较。胆碱乙酰转移酶免疫反应性位于精细的静脉曲张纤维中，这些纤维存在于视觉皮层的所有层中。标记纤维的密度在第I层最高，其中包含所有纤维的14%和所有静脉曲张的19.5%，并向深层下降。静脉曲张的数量减少更显着向更深的层比纤维的频率。这些分布模式非常一致，仅显示出轻微的个体内和个体间变异性。
The laminar distribution of cholinergic axons was analyzed quantitatively in the visual cortex of adult cats by using immunocytochemistry with a monoclonal antibody against choline acetyltransferase (ChAT). ChAT (+) fibers and varicosities were counted at different locations within area 17 and the distribution patterns in various animals were compared. Choline acetyl‐transferase‐immunoreactivity was localized in fine, varicose fibers, which were present in all layers of the visual cortex. The density of labeled fibers was highest in layer I, which contained 14% of all fibers and 19.5% of all varicosities, and decreased toward deeper layers. The number of varicosities decreased more markedly toward deeper layers than the frequency of fibers. These distribution patterns were very consistent, showing only slight intra‐ and interindividual variability.