Accelerated inactivation of cardiac L‐type calcium channels triggered by anaesthetic‐induced preconditioning
Accelerated inactivation of cardiac L‐type calcium channels triggered by anaesthetic‐induced preconditioning
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DOI：
10.1111/j.1476-5381.2008.00026.x
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发表时间：
2009-02
影响因子：
7.3
通讯作者：
A. Tampo;CS Hogan;F. Sedlic;Z. Bosnjak;W. Kwok
中科院分区：
文献类型：
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作者：
A. Tampo;CS Hogan;F. Sedlic;Z. Bosnjak;W. Kwok
背景和目的：麻醉诱导预适应（APC）对心肌缺血的保护作用已得到证实。然而，APC对Ca2+过载衰减的机制尚不清楚。研究了异氟烷APC对心脏L型Ca通道的影响。
Background and purpose: Cardioprotection against ischaemia by anaesthetic‐induced preconditioning (APC) is well established. However, the mechanism underlying Ca2+ overload attenuation by APC is unknown. The effects of APC by isoflurane on the cardiac L‐type Ca channel were investigated.