Imaging current flow in lobster nerve cord using the acoustoelectric effect
Imaging current flow in lobster nerve cord using the acoustoelectric effect
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DOI:
10.1063/1.2724901
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发表时间:
2007-04-16
影响因子:
4
通讯作者:
O'Donnell, Matthew
中科院分区:
文献类型:
--
作者:
Witte, Russell;Olafsson, Ragnar;O'Donnell, Matthew
Ultrasound traversing a biologic fluid or tissue generates a local change in electrical conductivity known as the acoustoelectric effect. The authors exploit this interaction to image ionic current injected into the abdominal segment of the lobster nerve cord. A pair of recording electrodes detected the acoustoelectric signal induced by pulses of focused ultrasound (1.4 or 7.5 MHz). The signal was linear with injected current at 2 MPa (0.7 mu V/mA cm(2)) and pressure at 75 mA/cm(2) (23 mu V/MPa). Acoustoelectric imaging of biocurrents potentially enhances spatial resolution of traditional electrophysiology and merits further study as an imaging modality for neural applications.