CLONING AND SEQUENCE-ANALYSIS OF CDNA FOR HUMAN PREALBUMIN
CLONING AND SEQUENCE-ANALYSIS OF CDNA FOR HUMAN PREALBUMIN
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DOI：
10.1016/0006-291x(84)91590-0
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发表时间：
1984-01-01
影响因子：
3.1
通讯作者：
ARAKI, S
中科院分区：
文献类型：
--
作者：
MITA, S;MAEDA, S;ARAKI, S
从人肝cDNA文库中克隆了编码人前白蛋白的cDNA（互补DNA）。该DNA序列编码由147个氨基酸组成的多肽，包括完整的人前白蛋白序列和推定的信号序列。这一前白蛋白cDNA序列的阐明有望促进家族性淀粉样多发性神经病的产前诊断。
A cDNA (complementary DNA) coding for human prealbumin has been cloned from a cDNA library prepared from human liver. The DNA sequence codes for a polypeptide which consists of 147 amino acids including a whole human prealbumin sequence and a putative signal sequence. The elucidation of this prealbumin cDNA sequence is expected to facilitate a prenatal diagnosis of familial amyloidotic polyneuropathy.