Stability of heterogeneous elastography phantoms made from oil dispersions in aqueous gels
Stability of heterogeneous elastography phantoms made from oil dispersions in aqueous gels
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DOI：
10.1016/j.ultrasmedbio.2005.10.009
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发表时间：
2006-02-01
影响因子：
2.9
通讯作者：
Frank, GR
中科院分区：
文献类型：
--
作者：
Madsen, EL;Hobson, MA;Frank, GR
制作了一组五个具有圆柱形内含物的模拟组织模型，用于评估几何形状和弹性特性的长期稳定性以及评估弹性特性测定的准确性。基础水性材料是明胶或琼脂和明胶的混合物。通过选择由微小红花油滴组成的体积百分比来控制刚度。数月以来，气缸直径的变化保持在 1% 或 2% 以内。模型弹性图的应变比在数月内保持稳定，这意味着弹性对比也是稳定的。用于测量杨氏模量的测试样品（称为生产样品）是在制造每个模型时制作的，并且彼此分开存储。每个生产样品都是均质的并且由内含物材料或背景材料组成。对于所有五个体模，发现使用生产样品确定的杨氏模量值计算的弹性对比度准确地代表了相应体模中的真实弹性对比度。这一发现的事实是，使用从体模本身切下的样品确定的（真实）弹性对比度与使用均质生产样品获得的弹性对比度一致。 （电子邮件：elmadsen@wisc.edu） (C) 2006 年世界超声医学与生物学联合会。
A set of five tissue-mimicking phantoms with cylindrical inclusions were produced for assessing long-term stability of geometry and elastic properties and assessing accuracy of determination of elastic properties. The base aqueous materials were either gelatin or a mixture of agar and gelatin. Stiffness was controlled by selection of the volume percent consisting of microscopic safflower oil droplets. Cylinder diameters remained unchanged within 1% or 2% over many months. Strain ratios from elastograms of the phantoms were stable over many months, implying that elastic contrasts were also stable. Test samples, called production samples, for measurement of Young's moduli were made at the time of manufacture of each phantom and were stored separately from one another. Each production sample was homogeneous and consisted of either inclusion material or background material. For all five phantoms, it was found that the elastic contrast computed using Young's modulus values determined using the production samples accurately represented the true elastic contrasts in the corresponding phantom. This finding was established by the fact that the (true) elastic contrasts determined using samples excised from the phantoms themselves agreed with the elastic contrasts obtained using the homogeneous production samples. (E-mail: elmadsen@wisc.edu) (C) 2006 World Federation for Ultrasound in Medicine & Biology.