Contribution of Genomics to Gene Discovery in Plant Abiotic Stress Responses
Contribution of Genomics to Gene Discovery in Plant Abiotic Stress Responses
复制标题
基因组学对植物非生物胁迫反应中基因发现的贡献
DOI：
10.1093/mp/sss085
复制
发表时间：
2012-11-01
期刊：
影响因子：
27.5
通讯作者：
Lam-Son Phan Tran
中科院分区：
文献类型：
--
作者：
Ma, Yun;Qin, Feng;Lam-Son Phan Tran
在干旱和高盐度等不利环境条件下维持农业生产是一项重大挑战。植物对环境胁迫反应的关键基因和信号转导途径的发现将在制定作物遗传改良策略以应对这一挑战方面发挥重要作用。作物功能基因组学对非生物胁迫相关基因的鉴定做出了巨大贡献。当前基因组技术的进步为在全基因组水平上识别胁迫相关基因提供了有效和高通量的方法，特别是在几种模型和作物物种的完整基因组序列可用的情况下。遗传数据库资源的发展使得生物信息学方法能够基于同源性和同线性来识别跨物种的耐压基因家族。此外，针对作物复杂性状基因座的全基因组关联研究（GWAS）促进了关键胁迫相关基因及其有利等位基因的发现。
Sustaining agricultural production under adverse environmental conditions, such as drought and high salinity, represents a major challenge. The discovery of key genes and signal transduction pathways underlying plant responses to environmental stress will play an important role in developing strategies for the genetic improvement of crops to address this challenge. Crop functional genomics has greatly contributed to the identification of abiotic stress-related genes. Current advances in genomic technologies now provide effective and high-throughput methods for identifying stress-related genes at a genome-wide level, especially with the availability of the complete genomic sequence of several model and crop plant species. The development of genetic database resources has allowed bioinformatic approaches to identify stress-tolerant gene families across species based on homology and synteny. Additionally, genome-wide association studies (GWAS) for complex trait loci in crops have facilitated the discovery of critical stress-related genes and their favorable alleles.