Differential Impact of Lacunes and Microvascular Lesions on Poststroke Depression

Differential Impact of Lacunes and Microvascular Lesions on Poststroke Depression
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DOI：
10.1161/strokeaha.109.548545
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发表时间：
2009-11-01
期刊：
STROKE
影响因子：
8.3
通讯作者：
Giannakopoulos, Panteleimon
Giannakopoulos, Panteleimon
中科院分区：
医学1区
文献类型：
--
作者：
Santos, Micaela;Gold, Gabriel;Giannakopoulos, Panteleimon

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背景和目的：以前的研究认为卒中后抑郁（PSD）可能与累积的血管性脑病变有关，而与单个大梗死的位置和严重程度无关。我们对41例前瞻性记录和连续尸检的卒中病例中所有类型的微血管病变和腔隙进行了详细分析。
Background and Purpose-Previous studies have postulated that poststroke depression (PSD) might be related to cumulative vascular brain pathology rather than to the location and severity of a single macroinfarct. We performed a detailed analysis of all types of microvascular lesions and lacunes in 41 prospectively documented and consecutively autopsied stroke cases.Methods-Only cases with first-onset depression